2EF1

Crystal structure of the extracellular domain of human CD38

Replaces:  2DF1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
B	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EPE A 301

Chain	Residue
A	ARG127
A	LEU157
A	THR158
A	SER220
A	THR221
A	HOH345
A	HOH355

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EPE B 302

Chain	Residue
B	SER220
B	THR221
B	HOH340
B	HOH347
B	ARG127
B	LEU157

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"evidences":[{"source":"PubMed","id":"7961800","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1r16

Chain	Residue	Details
A	GLU226
A	GLU146

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1r16

Chain	Residue	Details
B	GLU226
B	GLU146

---