2E9F

Crystal Structure of T.th.HB8 Argininosuccinate lyase complexed with L-Arginine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004056	molecular_function	argininosuccinate lyase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006526	biological_process	arginine biosynthetic process
A	0016829	molecular_function	lyase activity
A	0042450	biological_process	arginine biosynthetic process via ornithine
B	0003824	molecular_function	catalytic activity
B	0004056	molecular_function	argininosuccinate lyase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006526	biological_process	arginine biosynthetic process
B	0016829	molecular_function	lyase activity
B	0042450	biological_process	arginine biosynthetic process via ornithine
C	0003824	molecular_function	catalytic activity
C	0004056	molecular_function	argininosuccinate lyase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006526	biological_process	arginine biosynthetic process
C	0016829	molecular_function	lyase activity
C	0042450	biological_process	arginine biosynthetic process via ornithine
D	0003824	molecular_function	catalytic activity
D	0004056	molecular_function	argininosuccinate lyase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006526	biological_process	arginine biosynthetic process
D	0016829	molecular_function	lyase activity
D	0042450	biological_process	arginine biosynthetic process via ornithine

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ARG B 491

Chain	Residue
A	HIS159
B	ASP84
B	ARG110
B	ASN111
B	VAL114
B	TYR320
B	GLN325
B	LYS328

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ARG B 492

Chain	Residue
A	ARG110
A	ASN111
A	VAL114
A	TYR320
A	GLN325
A	LYS328
B	HIS159
A	SER24

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ARG B 493

Chain	Residue
C	HIS159
D	ASN111
D	VAL114
D	TYR320
D	GLN325
D	LYS328

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site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ARG B 494

Chain	Residue
B	HOH1106
C	ASP84
C	ARG110
C	ASN111
C	VAL114
C	TYR320
C	GLN325
C	LYS328
D	HIS159

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Functional Information from PROSITE/UniProt

site_id	PS00163
Number of Residues	10
Details	FUMARATE_LYASES Fumarate lyases signature. GSsiMpQKkN

Chain	Residue	Details
A	GLY279-ASN288

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