2E81

Cytochrome c Nitrite Reductase from Wolinella succinogenes with bound intermediate hydroxylamine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0009061	biological_process	anaerobic respiration
A	0016491	molecular_function	oxidoreductase activity
A	0019645	biological_process	anaerobic electron transport chain
A	0020037	molecular_function	heme binding
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0042128	biological_process	nitrate assimilation
A	0042279	molecular_function	nitrite reductase (cytochrome, ammonia-forming) activity
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 513

Chain	Residue
A	GLU217
A	TYR218
A	LYS274
A	GLN276
A	HOH1610
A	HOH1740

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE YT3 A 801

Chain	Residue
A	HOH1833
A	HOH1834
A	HOH1835
A	HOH1839
A	GLU52
A	ASP444
A	HOH1683

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE YT3 A 802

Chain	Residue
A	PRO99
A	HEM1510
A	HEM1511
A	HOH1693
A	HOH1752
A	HOH1842
A	HOH1843

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE YT3 A 803

Chain	Residue
A	GLU408
A	GLU408
A	HEM1512
A	HEM1512
A	HOH1899
A	HOH1899

---

site_id	AC5
Number of Residues	25
Details	BINDING SITE FOR RESIDUE HEM A 1508

Chain	Residue
A	TYR96
A	ASN97
A	ASP108
A	ASN109
A	THR112
A	ARG114
A	THR115
A	LEU126
A	CYS130
A	CYS133
A	LYS134
A	CYS214
A	HIS215
A	TYR218
A	HIS277
A	ALA398
A	HIS400
A	HOA704
A	HEM1510
A	HOH1552
A	HOH1555
A	HOH1576
A	HOH1578
A	HOH1582
A	HOH1628

---

site_id	AC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM A 1509

Chain	Residue
A	TYR57
A	GLN60
A	TRP64
A	GLY167
A	CYS168
A	CYS171
A	HIS172
A	LEU179
A	HIS203
A	ARG207
A	MET300
A	TYR302
A	TYR310
A	SER311
A	HIS313
A	HEM1510
A	HOH1877

---

site_id	AC7
Number of Residues	24
Details	BINDING SITE FOR RESIDUE HEM A 1510

Chain	Residue
A	SER70
A	PRO99
A	ARG100
A	GLY101
A	HIS102
A	TYR104
A	ALA105
A	ASP108
A	CYS133
A	LYS134
A	ILE166
A	VAL210
A	CYS211
A	CYS214
A	HIS215
A	VAL315
A	GLY316
A	YT3802
A	HEM1508
A	HEM1509
A	HEM1511
A	HOH1550
A	HOH1551
A	HOH1752

---

site_id	AC8
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM A 1511

Chain	Residue
A	HIS299
A	ASN317
A	LEU319
A	HIS400
A	GLY401
A	PHE403
A	PHE404
A	HIS405
A	YT3802
A	HEM1510
A	HEM1512
A	HOH1753
A	HOH1843
A	PRO99
A	TRP280
A	TYR283
A	HIS288
A	SER294
A	CYS295
A	CYS298

---

site_id	AC9
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM A 1512

Chain	Residue
A	ILE287
A	HIS288
A	VAL293
A	PRO318
A	SER325
A	CYS326
A	CYS329
A	HIS330
A	HIS330
A	LEU337
A	LYS344
A	PRO407
A	YT3803
A	YT3803
A	HEM1511
A	HOH1754
A	HOH1899

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE HOA A 704

Chain	Residue
A	ARG114
A	HIS277
A	HEM1508
A	HOH1513
A	HOH1514
A	HOH1515

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PDB","id":"1FS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FS8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FS9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E81","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BNF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BNG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BNH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BNJ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	10
Details	Binding site: {"description":"covalent","evidences":[{"source":"PDB","id":"1FS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FS8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FS9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E81","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BNF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BNG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BNH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BNJ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PDB","id":"1FS7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FS8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FS9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E81","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BNF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BNG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BNH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BNJ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3BNF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---