2E7P
Crystal structure of the holo form of glutaredoxin C1 from populus tremula x tremuloides
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0015038 | molecular_function | glutathione disulfide oxidoreductase activity |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0015038 | molecular_function | glutathione disulfide oxidoreductase activity |
| B | 0034599 | biological_process | cellular response to oxidative stress |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0015038 | molecular_function | glutathione disulfide oxidoreductase activity |
| C | 0034599 | biological_process | cellular response to oxidative stress |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051536 | molecular_function | iron-sulfur cluster binding |
| C | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0015038 | molecular_function | glutathione disulfide oxidoreductase activity |
| D | 0034599 | biological_process | cellular response to oxidative stress |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051536 | molecular_function | iron-sulfur cluster binding |
| D | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FES A 1201 |
| Chain | Residue |
| A | CYS30 |
| A | GLY31 |
| A | GSH1001 |
| C | CYS30 |
| C | GLY31 |
| C | TYR32 |
| C | GSH1000 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE GSH A 1001 |
| Chain | Residue |
| A | GLN62 |
| A | THR73 |
| A | VAL74 |
| A | PRO75 |
| A | GLY86 |
| A | CYS87 |
| A | ASP88 |
| A | FES1201 |
| A | HOH1208 |
| A | HOH1209 |
| A | HOH1214 |
| A | HOH1217 |
| A | HOH1227 |
| A | HOH1238 |
| C | GLY31 |
| C | HOH1002 |
| C | HOH1031 |
| A | LYS27 |
| A | CYS30 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GSH B 1002 |
| Chain | Residue |
| A | THR73 |
| B | LYS27 |
| B | CYS30 |
| B | TYR32 |
| B | GLN62 |
| B | THR73 |
| B | VAL74 |
| B | PRO75 |
| B | GLY86 |
| B | CYS87 |
| B | ASP88 |
| B | HOH1015 |
| B | HOH1033 |
| B | HOH1047 |
| C | ASN34 |
| C | HOH1031 |
| C | HOH1065 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE GSH C 1000 |
| Chain | Residue |
| A | GLY31 |
| A | FES1201 |
| A | HOH1244 |
| C | LYS27 |
| C | TYR29 |
| C | CYS30 |
| C | GLN62 |
| C | THR73 |
| C | VAL74 |
| C | PRO75 |
| C | GLY86 |
| C | CYS87 |
| C | ASP88 |
| C | HOH1038 |
| C | HOH1063 |
| C | HOH1089 |
| C | HOH1095 |
| D | THR73 |
| D | GSH1003 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE GSH D 1003 |
| Chain | Residue |
| A | THR28 |
| A | ASN34 |
| A | HOH1244 |
| C | GSH1000 |
| D | LYS27 |
| D | CYS30 |
| D | TYR32 |
| D | GLN62 |
| D | THR73 |
| D | VAL74 |
| D | PRO75 |
| D | GLY86 |
| D | CYS87 |
| D | ASP88 |
| D | HOH1004 |
| D | HOH1031 |
| D | HOH1040 |
| D | HOH1043 |
Functional Information from PROSITE/UniProt
| site_id | PS00194 |
| Number of Residues | 19 |
| Details | THIOREDOXIN_1 Thioredoxin family active site. VVvFSktYCGYCNrVkqlL |
| Chain | Residue | Details |
| A | VAL22-LEU40 |
