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2E7A

TNF Receptor Subtype One-selective TNF Mutant with Antagonistic Activity

Functional Information from GO Data
ChainGOidnamespacecontents
A0005164molecular_functiontumor necrosis factor receptor binding
A0006955biological_processimmune response
A0016020cellular_componentmembrane
B0005164molecular_functiontumor necrosis factor receptor binding
B0006955biological_processimmune response
B0016020cellular_componentmembrane
C0005164molecular_functiontumor necrosis factor receptor binding
C0006955biological_processimmune response
C0016020cellular_componentmembrane
Functional Information from PROSITE/UniProt
site_idPS00251
Number of Residues17
DetailsTNF_1 TNF family signature. LvVPsEGLYLIysQVlF
ChainResidueDetails
ALEU48-PHE64

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsCARBOHYD: O-linked (GalNAc...) serine; in soluble form => ECO:0000269|PubMed:8631363
ChainResidueDetails
ASER4
BSER4
CSER4

218853

PDB entries from 2024-04-24

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