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2E3P

Crystal structure of CERT START domain in complex with C16-cearmide (P1)

Functional Information from GO Data
ChainGOidnamespacecontents
A0008289molecular_functionlipid binding
B0008289molecular_functionlipid binding
Functional Information from PDB Data
site_idAC1
Number of Residues13
DetailsBINDING SITE FOR RESIDUE 16C A 600
ChainResidue
APHE436
AVAL525
ATYR553
ALEU568
ATYR576
AARG442
AGLU446
AGLN467
AHIS469
AVAL472
AALA475
ATYR482
AASN504

site_idAC2
Number of Residues14
DetailsBINDING SITE FOR RESIDUE 16C B 700
ChainResidue
BPHE436
BARG442
BGLU446
BGLN467
BHIS469
BVAL472
BALA475
BARG478
BTYR482
BASN504
BVAL525
BTYR553
BVAL571
BTYR576

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:18184806, ECO:0000269|PubMed:20036255
ChainResidueDetails
AVAL472
ATHR493
AGLN530
APHE579
BVAL472
BTHR493
BGLN530
BPHE579

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphotyrosine => ECO:0007744|PubMed:23186163
ChainResidueDetails
AGLU372
BGLU372

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
AGLU373
ATHR380
BGLU373
BTHR380

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648
ChainResidueDetails
AASN377
BASN377

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PDB entries from 2024-07-24

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