2E2K

Helicobacter pylori formamidase AmiF contains a fine-tuned cysteine-glutamate-lysine catalytic triad

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004328	molecular_function	formamidase activity
A	0016787	molecular_function	hydrolase activity
A	0033388	biological_process	putrescine biosynthetic process from arginine
A	0050126	molecular_function	N-carbamoylputrescine amidase activity
B	0004328	molecular_function	formamidase activity
B	0016787	molecular_function	hydrolase activity
B	0033388	biological_process	putrescine biosynthetic process from arginine
B	0050126	molecular_function	N-carbamoylputrescine amidase activity
C	0004328	molecular_function	formamidase activity
C	0016787	molecular_function	hydrolase activity
C	0033388	biological_process	putrescine biosynthetic process from arginine
C	0050126	molecular_function	N-carbamoylputrescine amidase activity
D	0004328	molecular_function	formamidase activity
D	0016787	molecular_function	hydrolase activity
D	0033388	biological_process	putrescine biosynthetic process from arginine
D	0050126	molecular_function	N-carbamoylputrescine amidase activity
E	0004328	molecular_function	formamidase activity
E	0016787	molecular_function	hydrolase activity
E	0033388	biological_process	putrescine biosynthetic process from arginine
E	0050126	molecular_function	N-carbamoylputrescine amidase activity
F	0004328	molecular_function	formamidase activity
F	0016787	molecular_function	hydrolase activity
F	0033388	biological_process	putrescine biosynthetic process from arginine
F	0050126	molecular_function	N-carbamoylputrescine amidase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	246
Details	Domain: {"description":"CN hydrolase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00054","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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