2DY3
Crystal Structure of alanine racemase from Corynebacterium glutamicum
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006522 | biological_process | alanine metabolic process |
| A | 0008784 | molecular_function | alanine racemase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0030632 | biological_process | D-alanine biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006522 | biological_process | alanine metabolic process |
| B | 0008784 | molecular_function | alanine racemase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0030632 | biological_process | D-alanine biosynthetic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006522 | biological_process | alanine metabolic process |
| C | 0008784 | molecular_function | alanine racemase activity |
| C | 0009252 | biological_process | peptidoglycan biosynthetic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0030632 | biological_process | D-alanine biosynthetic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006522 | biological_process | alanine metabolic process |
| D | 0008784 | molecular_function | alanine racemase activity |
| D | 0009252 | biological_process | peptidoglycan biosynthetic process |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0030632 | biological_process | D-alanine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PLP A 401 |
| Chain | Residue |
| A | VAL32 |
| A | LEU217 |
| A | TYR346 |
| B | ASP305 |
| B | HOH567 |
| A | LYS34 |
| A | TYR38 |
| A | TRP80 |
| A | HIS158 |
| A | ASN198 |
| A | SER199 |
| A | ARG214 |
| A | GLY216 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PLP B 401 |
| Chain | Residue |
| A | HOH556 |
| B | VAL32 |
| B | LYS34 |
| B | TYR38 |
| B | TRP80 |
| B | HIS158 |
| B | ASN198 |
| B | SER199 |
| B | ARG214 |
| B | PRO215 |
| B | GLY216 |
| B | LEU217 |
| B | TYR346 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PLP C 401 |
| Chain | Residue |
| C | VAL32 |
| C | LYS34 |
| C | TYR38 |
| C | TRP80 |
| C | HIS158 |
| C | ASN198 |
| C | SER199 |
| C | PRO200 |
| C | ARG214 |
| C | PRO215 |
| C | GLY216 |
| C | LEU217 |
| C | TYR346 |
| C | HOH535 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PLP D 401 |
| Chain | Residue |
| C | HOH536 |
| D | VAL32 |
| D | LYS34 |
| D | TYR38 |
| D | TRP80 |
| D | HIS158 |
| D | ASN198 |
| D | SER199 |
| D | ARG214 |
| D | PRO215 |
| D | GLY216 |
| D | LEU217 |
| D | TYR346 |
| D | HOH463 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor; specific for D-alanine","evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine"} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bd0 |
| Chain | Residue | Details |
| A | CYS303 | |
| B | LYS34 | |
| B | ARG129 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bd0 |
| Chain | Residue | Details |
| A | LYS34 | |
| A | ARG129 | |
| B | CYS303 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bd0 |
| Chain | Residue | Details |
| C | CYS303 | |
| D | LYS34 | |
| D | ARG129 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bd0 |
| Chain | Residue | Details |
| D | CYS303 | |
| C | LYS34 | |
| C | ARG129 |
