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2DVW

Structure of the Oncoprotein Gankyrin in Complex with S6 ATPase of the 26S Proteasome

Functional Information from GO Data
ChainGOidnamespacecontents
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0000502cellular_componentproteasome complex
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006915biological_processapoptotic process
A0007253biological_processcytoplasmic sequestering of NF-kappaB
A0008540cellular_componentproteasome regulatory particle, base subcomplex
A0030307biological_processpositive regulation of cell growth
A0031398biological_processpositive regulation of protein ubiquitination
A0032088biological_processnegative regulation of NF-kappaB transcription factor activity
A0032436biological_processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
A0043066biological_processnegative regulation of apoptotic process
A0043409biological_processnegative regulation of MAPK cascade
A0043518biological_processnegative regulation of DNA damage response, signal transduction by p53 class mediator
A0045111cellular_componentintermediate filament cytoskeleton
A0045737biological_processpositive regulation of cyclin-dependent protein serine/threonine kinase activity
A0070682biological_processproteasome regulatory particle assembly
A0090201biological_processnegative regulation of release of cytochrome c from mitochondria
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
BLYS397
BLYS401

227111

PDB entries from 2024-11-06

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