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2DPM

DPNM DNA ADENINE METHYLTRANSFERASE FROM STREPTOCCOCUS PNEUMONIAE COMPLEXED WITH S-ADENOSYLMETHIONINE

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0003677molecular_functionDNA binding
A0006298biological_processmismatch repair
A0008168molecular_functionmethyltransferase activity
A0009007molecular_functionsite-specific DNA-methyltransferase (adenine-specific) activity
A0009307biological_processDNA restriction-modification system
A0032259biological_processmethylation
A0043565molecular_functionsequence-specific DNA binding
A1904047molecular_functionS-adenosyl-L-methionine binding
Functional Information from PDB Data
site_idAC1
Number of Residues1
DetailsBINDING SITE FOR RESIDUE HG A 301
ChainResidue
ACYS70

site_idAC2
Number of Residues22
DetailsBINDING SITE FOR RESIDUE SAM A 300
ChainResidue
AGLY46
AGLY47
AALA48
AASP62
APHE63
AGLY176
AASP177
APHE178
AASP194
APRO195
ATRP17
AHOH402
AHOH409
AHOH444
AHOH902
ATHR18
AGLY19
AGLY20
ALYS21
APHE43
AVAL44
AGLY45

Functional Information from PROSITE/UniProt
site_idPS00092
Number of Residues7
DetailsN6_MTASE N-6 Adenine-specific DNA methylases signature. VYFDPPY
ChainResidueDetails
AVAL191-TYR197

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:9862809, ECO:0007744|PDB:2DPM
ChainResidueDetails
ATRP17
AGLY46
AASP62
AASP177
APHE178
AASP194

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0007744|PDB:2DPM
ChainResidueDetails
ALYS21

226707

PDB entries from 2024-10-30

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