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2DLC

Crystal structure of the ternary complex of yeast tyrosyl-tRNA synthetase

Functional Information from GO Data
ChainGOidnamespacecontents
X0000166molecular_functionnucleotide binding
X0003729molecular_functionmRNA binding
X0004812molecular_functionaminoacyl-tRNA ligase activity
X0004831molecular_functiontyrosine-tRNA ligase activity
X0005515molecular_functionprotein binding
X0005524molecular_functionATP binding
X0005634cellular_componentnucleus
X0005737cellular_componentcytoplasm
X0006412biological_processtranslation
X0006418biological_processtRNA aminoacylation for protein translation
X0006437biological_processtyrosyl-tRNA aminoacylation
X0010494cellular_componentcytoplasmic stress granule
X1990825molecular_functionsequence-specific mRNA binding
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG X 801
ChainResidue
XALA47
XTHR49
XTYR56
XTYR101
XYMP601

site_idAC2
Number of Residues27
DetailsBINDING SITE FOR RESIDUE YMP X 601
ChainResidue
XALA47
XHIS53
XGLY55
XTYR56
XLEU76
XALA78
XHIS81
XVAL156
XTYR170
XGLN174
XASP177
XGLN186
XGLY188
XGLY189
XASP191
XGLN192
XASN216
XPRO217
XMET218
XVAL219
XMG801
XHOH821
XHOH834
XTYR43
XTRP44
XGLY45
XTHR46

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues5
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P54577
ChainResidueDetails
XTRP44
XPRO171
XALA175
XGLU178
XARG193

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N-acetylserine => ECO:0000269|Ref.7
ChainResidueDetails
XSER3

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956
ChainResidueDetails
XLYS236

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18407956
ChainResidueDetails
XPRO360

226707

PDB entries from 2024-10-30

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