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2DEJ

Crystal Structure of galaktokinase from Pyrococcus horikoshii with AMP-PN and galactose

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0004335molecular_functiongalactokinase activity
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006012biological_processgalactose metabolic process
A0016301molecular_functionkinase activity
A0016310biological_processphosphorylation
A0016773molecular_functionphosphotransferase activity, alcohol group as acceptor
A0046835biological_processcarbohydrate phosphorylation
A0046872molecular_functionmetal ion binding
Functional Information from PROSITE/UniProt
site_idPS00106
Number of Residues12
DetailsGALACTOKINASE Galactokinase signature. GRvNLIGEHtDY
ChainResidueDetails
AGLY8-TYR19

site_idPS00627
Number of Residues12
DetailsGHMP_KINASES_ATP GHMP kinases putative ATP-binding domain. LPlGaGLSSSAS
ChainResidueDetails
ALEU96-SER107

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton acceptor => ECO:0000305
ChainResidueDetails
AASP149

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING:
ChainResidueDetails
AGLU15
ASER47
AGLY99
ATYR198

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00246
ChainResidueDetails
ASER105
AGLU137

site_idSWS_FT_FI4
Number of Residues1
DetailsSITE: Transition state stabilizer => ECO:0000305
ChainResidueDetails
AARG9

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1fwk
ChainResidueDetails
ASER195

226707

PDB entries from 2024-10-30

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