2DBT
Crystal structure of chitinase C from Streptomyces griseus HUT6037
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0004568 | molecular_function | chitinase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006032 | biological_process | chitin catabolic process |
| A | 0006952 | biological_process | defense response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0030246 | molecular_function | carbohydrate binding |
| A | 0050832 | biological_process | defense response to fungus |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0004568 | molecular_function | chitinase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006032 | biological_process | chitin catabolic process |
| B | 0006952 | biological_process | defense response |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016998 | biological_process | cell wall macromolecule catabolic process |
| B | 0030246 | molecular_function | carbohydrate binding |
| B | 0050832 | biological_process | defense response to fungus |
| C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| C | 0004568 | molecular_function | chitinase activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006032 | biological_process | chitin catabolic process |
| C | 0006952 | biological_process | defense response |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016998 | biological_process | cell wall macromolecule catabolic process |
| C | 0030246 | molecular_function | carbohydrate binding |
| C | 0050832 | biological_process | defense response to fungus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EPE A 295 |
| Chain | Residue |
| A | GLU147 |
| A | GLN269 |
| A | ILE187 |
| A | GLN188 |
| A | LEU189 |
| A | SER190 |
| A | ASN194 |
| A | TYR227 |
| A | ILE256 |
| A | ASN257 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE EPE B 295 |
| Chain | Residue |
| B | HIS146 |
| B | GLU147 |
| B | ILE187 |
| B | GLN188 |
| B | LEU189 |
| B | SER190 |
| B | TYR227 |
| B | ILE256 |
| B | ASN257 |
| B | GLN269 |
| B | ARG273 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EPE C 295 |
| Chain | Residue |
| C | GLU147 |
| C | ILE187 |
| C | GLN188 |
| C | LEU189 |
| C | SER190 |
| C | ASN194 |
| C | TYR227 |
| C | ILE256 |
| C | ASN257 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details |
| Chain | Residue | Details |
| A | GLU156 |
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 819 |
| Chain | Residue | Details |
| A | GLU147 | promote heterolysis, proton acceptor, proton donor |
| A | GLU156 | activator, electrostatic stabiliser, increase nucleophilicity, proton acceptor, proton donor |
| A | ASN194 | steric role |
| site_id | MCSA2 |
| Number of Residues | 3 |
| Details | M-CSA 819 |
| Chain | Residue | Details |
| B | GLU147 | promote heterolysis, proton acceptor, proton donor |
| B | GLU156 | activator, electrostatic stabiliser, increase nucleophilicity, proton acceptor, proton donor |
| B | ASN194 | steric role |
| site_id | MCSA3 |
| Number of Residues | 3 |
| Details | M-CSA 819 |
| Chain | Residue | Details |
| C | GLU147 | promote heterolysis, proton acceptor, proton donor |
| C | GLU156 | activator, electrostatic stabiliser, increase nucleophilicity, proton acceptor, proton donor |
| C | ASN194 | steric role |
