2D74

Crystal structure of translation initiation factor aIF2betagamma heterodimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0001514	biological_process	selenocysteine incorporation
A	0001731	biological_process	formation of translation preinitiation complex
A	0003743	molecular_function	translation initiation factor activity
A	0003746	molecular_function	translation elongation factor activity
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006413	biological_process	translational initiation
A	0016259	biological_process	selenocysteine metabolic process
A	0016787	molecular_function	hydrolase activity
A	0035368	molecular_function	selenocysteine insertion sequence binding
A	0046872	molecular_function	metal ion binding
B	0001731	biological_process	formation of translation preinitiation complex
B	0001732	biological_process	formation of cytoplasmic translation initiation complex
B	0003729	molecular_function	mRNA binding
B	0003743	molecular_function	translation initiation factor activity
B	0005515	molecular_function	protein binding
B	0006412	biological_process	translation
B	0006413	biological_process	translational initiation
B	0031369	molecular_function	translation initiation factor binding

Functional Information from PDB Data

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:Q980A5, ECO:0000255\|HAMAP-Rule:MF_00119

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00119, ECO:0000269\|PubMed:16924118, ECO:0007744\|PDB:2DCU

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00119, ECO:0000269\|PubMed:16924118, ECO:0007744\|PDB:2D74, ECO:0007744\|PDB:2DCU