2D3M
Pentaketide chromone synthase complexed with coenzyme A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009813 | biological_process | flavonoid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0030639 | biological_process | polyketide biosynthetic process |
| A | 0042803 | molecular_function | protein homodimerization activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009813 | biological_process | flavonoid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0030639 | biological_process | polyketide biosynthetic process |
| B | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE COA A 500 |
| Chain | Residue |
| A | LYS68 |
| A | LEU280 |
| A | SER281 |
| A | SER284 |
| A | GLY321 |
| A | GLY322 |
| A | ARG323 |
| A | ALA324 |
| A | ILE325 |
| A | HOH2893 |
| A | HOH2895 |
| A | HIS71 |
| A | LYS75 |
| A | CSD177 |
| A | ASP220 |
| A | ILE223 |
| A | LEU227 |
| A | PHE228 |
| A | ILE267 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE COA B 501 |
| Chain | Residue |
| B | LYS68 |
| B | CSD177 |
| B | ASP220 |
| B | ILE223 |
| B | LEU227 |
| B | PHE228 |
| B | ILE267 |
| B | PHE278 |
| B | LEU280 |
| B | SER281 |
| B | LYS282 |
| B | SER284 |
| B | GLY321 |
| B | GLY322 |
| B | ARG323 |
| B | ALA324 |
| B | ILE325 |
| B | HOH3055 |
| B | HOH3110 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17462571","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Determines the polyketide chain length and product specificity"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Cysteine sulfinic acid (-SO2H)","evidences":[{"source":"PubMed","id":"17462571","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1cgk |
| Chain | Residue | Details |
| A | PHE228 | |
| A | ASN352 | |
| A | HIS319 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1cgk |
| Chain | Residue | Details |
| B | PHE228 | |
| B | ASN352 | |
| B | HIS319 |
