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2CZU

lipocalin-type prostaglandin D synthase

Functional Information from GO Data
ChainGOidnamespacecontents
A0001516biological_processprostaglandin biosynthetic process
A0004667molecular_functionprostaglandin-D synthase activity
A0005501molecular_functionretinoid binding
A0005504molecular_functionfatty acid binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005654cellular_componentnucleoplasm
A0005788cellular_componentendoplasmic reticulum lumen
A0005791cellular_componentrough endoplasmic reticulum
A0005794cellular_componentGolgi apparatus
A0006629biological_processlipid metabolic process
A0006631biological_processfatty acid metabolic process
A0006633biological_processfatty acid biosynthetic process
A0006693biological_processprostaglandin metabolic process
A0010467biological_processgene expression
A0016853molecular_functionisomerase activity
A0019371biological_processcyclooxygenase pathway
A0031965cellular_componentnuclear membrane
A0036094molecular_functionsmall molecule binding
A0043303biological_processmast cell degranulation
A0045187biological_processregulation of circadian sleep/wake cycle, sleep
A0048471cellular_componentperinuclear region of cytoplasm
A0051384biological_processresponse to glucocorticoid
A2000255biological_processnegative regulation of male germ cell proliferation
B0001516biological_processprostaglandin biosynthetic process
B0004667molecular_functionprostaglandin-D synthase activity
B0005501molecular_functionretinoid binding
B0005504molecular_functionfatty acid binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005654cellular_componentnucleoplasm
B0005788cellular_componentendoplasmic reticulum lumen
B0005791cellular_componentrough endoplasmic reticulum
B0005794cellular_componentGolgi apparatus
B0006629biological_processlipid metabolic process
B0006631biological_processfatty acid metabolic process
B0006633biological_processfatty acid biosynthetic process
B0006693biological_processprostaglandin metabolic process
B0010467biological_processgene expression
B0016853molecular_functionisomerase activity
B0019371biological_processcyclooxygenase pathway
B0031965cellular_componentnuclear membrane
B0036094molecular_functionsmall molecule binding
B0043303biological_processmast cell degranulation
B0045187biological_processregulation of circadian sleep/wake cycle, sleep
B0048471cellular_componentperinuclear region of cytoplasm
B0051384biological_processresponse to glucocorticoid
B2000255biological_processnegative regulation of male germ cell proliferation
Functional Information from PROSITE/UniProt
site_idPS00213
Number of Residues14
DetailsLIPOCALIN Lipocalin signature. NFQqdKFLGRWYSA
ChainResidueDetails
AASN33-ALA46

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsActive site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"19546224","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues4
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

246031

PDB entries from 2025-12-10

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