2CXE

Crystal structure of octameric ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) from Pyrococcus horikoshii OT3 (form-2 crystal)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0006196	biological_process	AMP catabolic process
A	0015977	biological_process	carbon fixation
A	0016491	molecular_function	oxidoreductase activity
A	0016829	molecular_function	lyase activity
A	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0006196	biological_process	AMP catabolic process
B	0015977	biological_process	carbon fixation
B	0016491	molecular_function	oxidoreductase activity
B	0016829	molecular_function	lyase activity
B	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0006196	biological_process	AMP catabolic process
C	0015977	biological_process	carbon fixation
C	0016491	molecular_function	oxidoreductase activity
C	0016829	molecular_function	lyase activity
C	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0006196	biological_process	AMP catabolic process
D	0015977	biological_process	carbon fixation
D	0016491	molecular_function	oxidoreductase activity
D	0016829	molecular_function	lyase activity
D	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
D	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_01133

Chain	Residue	Details
A	LYS160
A	HIS278
B	LYS160
B	HIS278
C	LYS160
C	HIS278
D	LYS160
D	HIS278

---

site_id	SWS_FT_FI2
Number of Residues	28
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01133

Chain	Residue	Details
A	LYS162
B	GLU189
B	ARG279
B	HIS311
B	SER348
B	GLN370
C	LYS162
C	ASP188
C	GLU189
C	ARG279
C	HIS311
A	ASP188
C	SER348
C	GLN370
D	LYS162
D	ASP188
D	GLU189
D	ARG279
D	HIS311
D	SER348
D	GLN370
A	GLU189
A	ARG279
A	HIS311
A	SER348
A	GLN370
B	LYS162
B	ASP188

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: via carbamate group => ECO:0000255|HAMAP-Rule:MF_01133

Chain	Residue	Details
A	LYS186
B	LYS186
C	LYS186
D	LYS186

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_01133

Chain	Residue	Details
A	LYS318
B	LYS318
C	LYS318
D	LYS318

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: N6-carboxylysine => ECO:0000255|HAMAP-Rule:MF_01133

Chain	Residue	Details
A	LYS186
B	LYS186
C	LYS186
D	LYS186

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
A	HIS311
A	HIS278
A	LYS186
A	LYS160
A	ASP188
A	LYS162

---

site_id	CSA2
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
B	HIS311
B	HIS278
B	LYS186
B	LYS160
B	ASP188
B	LYS162

---

site_id	CSA3
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
C	HIS311
C	HIS278
C	LYS186
C	LYS160
C	ASP188
C	LYS162

---

site_id	CSA4
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
D	HIS311
D	HIS278
D	LYS186
D	LYS160
D	ASP188
D	LYS162

---