Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2CE7

EDTA treated

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004176	molecular_function	ATP-dependent peptidase activity
A	0004222	molecular_function	metalloendopeptidase activity
A	0005524	molecular_function	ATP binding
A	0006508	biological_process	proteolysis
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
B	0004176	molecular_function	ATP-dependent peptidase activity
B	0004222	molecular_function	metalloendopeptidase activity
B	0005524	molecular_function	ATP binding
B	0006508	biological_process	proteolysis
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
C	0004176	molecular_function	ATP-dependent peptidase activity
C	0004222	molecular_function	metalloendopeptidase activity
C	0005524	molecular_function	ATP binding
C	0006508	biological_process	proteolysis
C	0016020	cellular_component	membrane
C	0016887	molecular_function	ATP hydrolysis activity
D	0004176	molecular_function	ATP-dependent peptidase activity
D	0004222	molecular_function	metalloendopeptidase activity
D	0005524	molecular_function	ATP binding
D	0006508	biological_process	proteolysis
D	0016020	cellular_component	membrane
D	0016887	molecular_function	ATP hydrolysis activity
E	0004176	molecular_function	ATP-dependent peptidase activity
E	0004222	molecular_function	metalloendopeptidase activity
E	0005524	molecular_function	ATP binding
E	0006508	biological_process	proteolysis
E	0016020	cellular_component	membrane
E	0016887	molecular_function	ATP hydrolysis activity
F	0004176	molecular_function	ATP-dependent peptidase activity
F	0004222	molecular_function	metalloendopeptidase activity
F	0005524	molecular_function	ATP binding
F	0006508	biological_process	proteolysis
F	0016020	cellular_component	membrane
F	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A1603

Chain	Residue
A	HIS423
A	HIS427
A	ASP500
A	HOH2043
A	HOH2044

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A1605

Chain	Residue
A	ADP1604
A	HOH2046

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B1606

Chain	Residue
B	ASP500
B	HOH2031
B	HIS423
B	HIS427

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B1608

Chain	Residue
B	ADP1607
B	HOH2033

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C1607

Chain	Residue
C	HIS423
C	HIS427
C	ASP500
C	HOH2026

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C1609

Chain	Residue
C	PRO203
C	ADP1608

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D1607

Chain	Residue
D	HIS423
D	HIS427
D	ASP500
D	HOH2030

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D1609

Chain	Residue
D	ADP1608
D	HOH2031
D	HOH2032
D	HOH2033

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E1603

Chain	Residue
E	HIS423
E	HIS427
E	ASP500
E	HOH2035

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG E1605

Chain	Residue
E	ADP1604
E	HOH2036
E	HOH2037
E	HOH2038

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F1606

Chain	Residue
F	HIS423
F	HIS427
F	ASP500
F	HOH2023

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F1608

Chain	Residue
F	ADP1607

site_id	BC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ADP A1604

Chain	Residue
A	ASP162
A	VAL163
A	GLY164
A	PRO202
A	GLY204
A	THR205
A	GLY206
A	LYS207
A	THR208
A	LEU209
A	HIS343
A	GLY367
A	ALA368
A	GLU371
A	MG1605
A	HOH2045
A	HOH2046

site_id	BC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE ADP B1607

Chain	Residue
B	ASP162
B	VAL163
B	GLY164
B	PRO203
B	GLY204
B	THR205
B	GLY206
B	LYS207
B	THR208
B	LEU209
B	ILE339
B	HIS343
B	GLY367
B	ALA368
B	GLU371
B	MG1608
B	HOH2032
B	HOH2033

site_id	BC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ADP C1608

Chain	Residue
C	ASP162
C	VAL163
C	GLY164
C	PRO202
C	PRO203
C	GLY204
C	THR205
C	GLY206
C	LYS207
C	THR208
C	LEU209
C	ILE339
C	HIS343
C	GLY367
C	ALA368
C	GLU371
C	MG1609

site_id	BC7
Number of Residues	19
Details	BINDING SITE FOR RESIDUE ADP D1608

Chain	Residue
D	LYS207
D	THR208
D	LEU209
D	HIS343
D	GLY367
D	ALA368
D	GLU371
D	MG1609
D	HOH2008
D	HOH2031
D	HOH2032
D	HOH2033
D	ASP162
D	VAL163
D	GLY164
D	PRO202
D	GLY204
D	THR205
D	GLY206

site_id	BC8
Number of Residues	18
Details	BINDING SITE FOR RESIDUE ADP E1604

Chain	Residue
E	ASP162
E	VAL163
E	GLY164
E	PRO202
E	GLY204
E	THR205
E	GLY206
E	LYS207
E	THR208
E	LEU209
E	ILE339
E	HIS343
E	GLY367
E	ALA368
E	GLU371
E	MG1605
E	HOH2036
E	HOH2038

site_id	BC9
Number of Residues	13
Details	BINDING SITE FOR RESIDUE ADP F1607

Chain	Residue
F	GLY164
F	PRO203
F	GLY204
F	THR205
F	GLY206
F	LYS207
F	THR208
F	LEU209
F	ILE339
F	HIS343
F	ALA368
F	GLU371
F	MG1608

Functional Information from PROSITE/UniProt

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. IiVMaATNrpdiLDpALl.R

Chain	Residue	Details
A	ILE300-ARG318

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: ACT_SITE => ECO:0000255\|HAMAP-Rule:MF_01458, ECO:0000269\|PubMed:16484367

Chain	Residue	Details
A	GLU424
B	GLU424
C	GLU424
D	GLU424
E	GLU424
F	GLU424

site_id	SWS_FT_FI2
Number of Residues	48
Details	BINDING: BINDING => ECO:0000269\|PubMed:16484367

Chain	Residue	Details
A	GLY164
B	GLY204
B	LEU209
B	HIS343
B	GLU371
B	HIS423
B	HIS427
B	ASP500
C	GLY164
C	GLY204
C	LEU209
A	GLY204
C	HIS343
C	GLU371
C	HIS423
C	HIS427
C	ASP500
D	GLY164
D	GLY204
D	LEU209
D	HIS343
D	GLU371
A	LEU209
D	HIS423
D	HIS427
D	ASP500
E	GLY164
E	GLY204
E	LEU209
E	HIS343
E	GLU371
E	HIS423
E	HIS427
A	HIS343
E	ASP500
F	GLY164
F	GLY204
F	LEU209
F	HIS343
F	GLU371
F	HIS423
F	HIS427
F	ASP500
A	GLU371
A	HIS423
A	HIS427
A	ASP500
B	GLY164

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)