2CDA
Sulfolobus solfataricus Glucose Dehydrogenase 1 in complex with NADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005534 | molecular_function | galactose binding |
| A | 0005536 | molecular_function | D-glucose binding |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019151 | molecular_function | galactose 1-dehydrogenase activity |
| A | 0019595 | biological_process | non-phosphorylated glucose catabolic process |
| A | 0033222 | molecular_function | xylose binding |
| A | 0033498 | biological_process | galactose catabolic process via D-galactonate |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047640 | molecular_function | aldose 1-dehydrogenase activity |
| A | 0047910 | molecular_function | galactose 1-dehydrogenase (NADP+) activity |
| A | 0047934 | molecular_function | glucose 1-dehydrogenase (NAD+) activity |
| A | 0047935 | molecular_function | glucose 1-dehydrogenase (NADP+) activity |
| A | 0047936 | molecular_function | glucose 1-dehydrogenase [NAD(P)+] activity |
| A | 0051262 | biological_process | protein tetramerization |
| A | 0070401 | molecular_function | NADP+ binding |
| A | 0070403 | molecular_function | NAD+ binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005534 | molecular_function | galactose binding |
| B | 0005536 | molecular_function | D-glucose binding |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019151 | molecular_function | galactose 1-dehydrogenase activity |
| B | 0019595 | biological_process | non-phosphorylated glucose catabolic process |
| B | 0033222 | molecular_function | xylose binding |
| B | 0033498 | biological_process | galactose catabolic process via D-galactonate |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047640 | molecular_function | aldose 1-dehydrogenase activity |
| B | 0047910 | molecular_function | galactose 1-dehydrogenase (NADP+) activity |
| B | 0047934 | molecular_function | glucose 1-dehydrogenase (NAD+) activity |
| B | 0047935 | molecular_function | glucose 1-dehydrogenase (NADP+) activity |
| B | 0047936 | molecular_function | glucose 1-dehydrogenase [NAD(P)+] activity |
| B | 0051262 | biological_process | protein tetramerization |
| B | 0070401 | molecular_function | NADP+ binding |
| B | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A1368 |
| Chain | Residue |
| A | CYS39 |
| A | HIS66 |
| A | GLU67 |
| A | GLN150 |
| A | HOH2075 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A1369 |
| Chain | Residue |
| A | CYS93 |
| A | CYS96 |
| A | CYS99 |
| A | CYS107 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B1368 |
| Chain | Residue |
| B | CYS39 |
| B | HIS66 |
| B | GLU67 |
| B | GLN150 |
| B | HOH2081 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B1369 |
| Chain | Residue |
| B | CYS93 |
| B | CYS96 |
| B | CYS99 |
| B | CYS107 |
| site_id | AC5 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAP A1367 |
| Chain | Residue |
| A | ASP154 |
| A | VAL187 |
| A | GLY188 |
| A | THR189 |
| A | PRO191 |
| A | ILE192 |
| A | ASN211 |
| A | ARG212 |
| A | ARG213 |
| A | ALA253 |
| A | THR254 |
| A | GLY255 |
| A | ALA256 |
| A | PHE277 |
| A | GLY278 |
| A | PHE279 |
| A | LEU305 |
| A | VAL306 |
| A | ASN307 |
| A | LYS354 |
| A | HOH2043 |
| A | HOH2071 |
| A | HOH2072 |
| A | HOH2073 |
| A | HOH2074 |
| site_id | AC6 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAP B1367 |
| Chain | Residue |
| B | ASP154 |
| B | VAL187 |
| B | GLY188 |
| B | THR189 |
| B | GLY190 |
| B | PRO191 |
| B | ILE192 |
| B | ASN211 |
| B | ARG212 |
| B | ARG213 |
| B | ALA253 |
| B | THR254 |
| B | GLY255 |
| B | ILE260 |
| B | PHE277 |
| B | GLY278 |
| B | PHE279 |
| B | LEU305 |
| B | VAL306 |
| B | ASN307 |
| B | LYS354 |
| B | HIS356 |
| B | HOH2076 |
| B | HOH2077 |
| B | HOH2078 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 44 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16556607","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02127","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| A | GLY40 | |
| A | THR41 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| B | GLY40 | |
| B | THR41 |
