2C6Y

Crystal structure of interleukin enhancer-binding factor 1 bound to DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0043565	molecular_function	sequence-specific DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
B	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A1099

Chain	Residue
A	LEU55
A	SER56
A	ASN58
A	PHE61

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B1096

Chain	Residue
B	LEU55
B	SER56
B	ASN58
B	PHE61
B	HOH2039

---

Functional Information from PROSITE/UniProt

site_id	PS00657
Number of Residues	14
Details	FORK_HEAD_1 Fork head domain signature 1. KPPYSYaqLivq.AI

Chain	Residue	Details
A	LYS3-ILE16

---

site_id	PS00658
Number of Residues	7
Details	FORK_HEAD_2 Fork head domain signature 2. WQNSIRH

Chain	Residue	Details
A	TRP47-HIS53

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	95
Details	DNA binding: {"description":"Fork-head","evidences":[{"source":"PROSITE-ProRule","id":"PRU00089","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	Region: {"description":"DNA-binding; major groove","evidences":[{"source":"PubMed","id":"16624804","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	13
Details	Region: {"description":"DNA-binding; minor groove","evidences":[{"source":"PubMed","id":"16624804","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16624804","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---