2C4M
Starch phosphorylase: structural studies explain oxyanion-dependent kinetic stability and regulatory control.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004645 | molecular_function | 1,4-alpha-oligoglucan phosphorylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0005980 | biological_process | glycogen catabolic process |
| A | 0008184 | molecular_function | glycogen phosphorylase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004645 | molecular_function | 1,4-alpha-oligoglucan phosphorylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0005980 | biological_process | glycogen catabolic process |
| B | 0008184 | molecular_function | glycogen phosphorylase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004645 | molecular_function | 1,4-alpha-oligoglucan phosphorylase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0005980 | biological_process | glycogen catabolic process |
| C | 0008184 | molecular_function | glycogen phosphorylase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004645 | molecular_function | 1,4-alpha-oligoglucan phosphorylase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0005980 | biological_process | glycogen catabolic process |
| D | 0008184 | molecular_function | glycogen phosphorylase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016757 | molecular_function | glycosyltransferase activity |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A1794 |
| Chain | Residue |
| A | GLY113 |
| A | GLY114 |
| A | PLP1634 |
| A | HOH2298 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 B1795 |
| Chain | Residue |
| B | SER174 |
| B | HOH2088 |
| B | HOH2300 |
| A | THR28 |
| A | ARG30 |
| A | LYS31 |
| B | ARG172 |
| B | ALA173 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 B1796 |
| Chain | Residue |
| A | ARG172 |
| A | ALA173 |
| A | SER174 |
| B | THR28 |
| B | ARG30 |
| B | LYS31 |
| B | HOH2301 |
| B | HOH2302 |
| B | HOH2303 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 B1797 |
| Chain | Residue |
| A | ARG141 |
| A | ARG234 |
| A | GLU235 |
| B | ARG141 |
| B | ARG234 |
| B | GLU235 |
| B | HOH2129 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 B1798 |
| Chain | Residue |
| B | GLY113 |
| B | GLY114 |
| B | PLP1634 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 C1796 |
| Chain | Residue |
| C | THR28 |
| C | ARG30 |
| C | LYS31 |
| C | HOH2019 |
| C | HOH2337 |
| D | ARG172 |
| D | ALA173 |
| D | SER174 |
| D | HOH2064 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 C1797 |
| Chain | Residue |
| C | ARG141 |
| C | ARG234 |
| C | GLU235 |
| C | HOH2091 |
| C | HOH2145 |
| C | HOH2338 |
| D | ARG141 |
| D | ARG234 |
| D | GLU235 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 C1798 |
| Chain | Residue |
| C | GLY113 |
| C | GLY114 |
| C | ARG523 |
| C | PLP1634 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 D1794 |
| Chain | Residue |
| C | ARG172 |
| C | ALA173 |
| C | SER174 |
| C | HOH2107 |
| D | THR28 |
| D | ARG30 |
| D | LYS31 |
| D | HOH2202 |
| D | HOH2203 |
| site_id | BC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PLP A1634 |
| Chain | Residue |
| A | GLY114 |
| A | TRP444 |
| A | LYS522 |
| A | ASN603 |
| A | VAL604 |
| A | THR630 |
| A | SER631 |
| A | LYS634 |
| A | PO41794 |
| A | HOH2056 |
| A | HOH2247 |
| site_id | BC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PLP B1634 |
| Chain | Residue |
| B | LEU69 |
| B | GLY114 |
| B | TRP444 |
| B | LYS522 |
| B | ASN603 |
| B | VAL604 |
| B | THR630 |
| B | SER631 |
| B | LYS634 |
| B | PO41798 |
| B | HOH2299 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B1801 |
| Chain | Residue |
| B | CYS180 |
| B | TYR262 |
| B | PHE353 |
| B | ARG355 |
| B | VAL356 |
| B | HOH2304 |
| B | HOH2305 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B1802 |
| Chain | Residue |
| B | TRP48 |
| B | THR51 |
| B | TYR55 |
| B | THR134 |
| B | VAL203 |
| B | GLY204 |
| B | THR205 |
| B | HOH2306 |
| site_id | BC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PLP C1634 |
| Chain | Residue |
| C | GLY114 |
| C | TRP444 |
| C | LYS522 |
| C | ASN603 |
| C | VAL604 |
| C | THR630 |
| C | SER631 |
| C | LYS634 |
| C | PO41798 |
| C | HOH2244 |
| C | HOH2336 |
| site_id | BC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO C1803 |
| Chain | Residue |
| C | TRP48 |
| C | THR51 |
| C | TYR55 |
| C | THR134 |
| C | VAL203 |
| C | GLY204 |
| C | THR205 |
| C | HOH2086 |
| C | HOH2340 |
| site_id | BC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PLP D1634 |
| Chain | Residue |
| D | GLY114 |
| D | TRP444 |
| D | ILE521 |
| D | LYS522 |
| D | ASN603 |
| D | VAL604 |
| D | GLY629 |
| D | THR630 |
| D | SER631 |
| D | LYS634 |
| D | HOH2148 |
| D | HOH2201 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A1795 |
| Chain | Residue |
| A | TYR136 |
| A | MET272 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A1796 |
| Chain | Residue |
| A | ARG52 |
| A | ARG172 |
| A | HOH2299 |
| A | HOH2300 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT A1797 |
| Chain | Residue |
| A | CYS180 |
| A | TYR262 |
| A | PHE353 |
| A | VAL356 |
| A | HOH2301 |
| A | HOH2302 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT A1798 |
| Chain | Residue |
| A | TRP48 |
| A | TYR55 |
| A | THR134 |
| A | VAL203 |
| A | GLY204 |
| A | THR205 |
| A | HOH2110 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A1799 |
| Chain | Residue |
| A | GLY114 |
| A | HIS334 |
| A | ASN437 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A1800 |
| Chain | Residue |
| A | GLU659 |
| A | GLU660 |
| A | ALA662 |
| A | TYR663 |
| A | MET760 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A1801 |
| Chain | Residue |
| A | HIS720 |
| A | GLY721 |
| D | HOH2186 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A1802 |
| Chain | Residue |
| A | THR79 |
| A | ASN80 |
| A | TYR198 |
| A | GLY199 |
| site_id | CC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A1803 |
| Chain | Residue |
| A | ARG355 |
| A | HOH2303 |
| site_id | CC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT B1799 |
| Chain | Residue |
| B | ARG355 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT B1800 |
| Chain | Residue |
| B | ASN80 |
| B | TYR198 |
| B | GLY199 |
| site_id | DC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT C1799 |
| Chain | Residue |
| C | ASN80 |
| C | GLY199 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT C1800 |
| Chain | Residue |
| C | CYS180 |
| C | PHE353 |
| C | ARG355 |
| C | HOH2114 |
| C | HOH2116 |
| C | HOH2339 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT C1801 |
| Chain | Residue |
| C | THR79 |
| C | ARG446 |
| C | MET447 |
| site_id | DC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT C1802 |
| Chain | Residue |
| C | ASP480 |
| C | ASP481 |
| C | LYS482 |
| site_id | DC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT D1795 |
| Chain | Residue |
| D | TRP48 |
| D | TYR55 |
| D | VAL203 |
| D | GLY204 |
| D | THR205 |
| D | HOH2049 |
| site_id | DC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT D1796 |
| Chain | Residue |
| D | ALA66 |
| D | ARG257 |
| D | GLN261 |
| D | HIS298 |
| D | HOH2204 |
| site_id | DC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT D1797 |
| Chain | Residue |
| D | TYR262 |
| D | PHE353 |
| D | ARG355 |
| D | VAL356 |
| D | HOH2205 |
| site_id | DC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT D1798 |
| Chain | Residue |
| D | TRP318 |
| D | ARG355 |
Functional Information from PROSITE/UniProt
| site_id | PS00102 |
| Number of Residues | 13 |
| Details | PHOSPHORYLASE Phosphorylase pyridoxal-phosphate attachment site. EASGtSnMKfmMN |
| Chain | Residue | Details |
| A | GLU626-ASN638 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1gpa |
| Chain | Residue | Details |
| A | LYS528 | |
| A | ARG523 | |
| A | LYS522 | |
| A | THR630 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1gpa |
| Chain | Residue | Details |
| B | LYS528 | |
| B | ARG523 | |
| B | LYS522 | |
| B | THR630 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1gpa |
| Chain | Residue | Details |
| C | LYS528 | |
| C | ARG523 | |
| C | LYS522 | |
| C | THR630 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1gpa |
| Chain | Residue | Details |
| D | LYS528 | |
| D | ARG523 | |
| D | LYS522 | |
| D | THR630 |
