2C43
STRUCTURE OF AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE- PHOSPHOPANTETHEINYL TRANSFERASE IN COMPLEX WITH COENZYME A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0008897 | molecular_function | holo-[acyl-carrier-protein] synthase activity |
| A | 0009258 | biological_process | 10-formyltetrahydrofolate catabolic process |
| A | 0015939 | biological_process | pantothenate metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019878 | biological_process | lysine biosynthetic process via aminoadipic acid |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051604 | biological_process | protein maturation |
| A | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A1317 |
| Chain | Residue |
| A | ASP139 |
| A | MET141 |
| A | GLU191 |
| A | COA1316 |
| A | HOH2176 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A1318 |
| Chain | Residue |
| A | GLN51 |
| A | ARG74 |
| A | ARG78 |
| site_id | AC3 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE COA A1316 |
| Chain | Residue |
| A | ARG96 |
| A | LYS99 |
| A | GLY100 |
| A | LYS101 |
| A | PRO102 |
| A | ASN118 |
| A | ILE119 |
| A | SER120 |
| A | HIS121 |
| A | ASP139 |
| A | TRP187 |
| A | GLU191 |
| A | ILE194 |
| A | LYS195 |
| A | GLY198 |
| A | GLY200 |
| A | LEU201 |
| A | LEU205 |
| A | MG1317 |
| A | HOH2036 |
| A | HOH2066 |
| A | HOH2102 |
| A | HOH2175 |
| A | HOH2176 |
| A | HOH2177 |
| A | HOH2178 |
| A | HOH2179 |
| A | HOH2180 |
| A | ARG57 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 13 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18022563","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2C43","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18022563","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2C43","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
