2C1Z
Structure and activity of a flavonoid 3-O glucosyltransferase reveals the basis for plant natural product modification
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008194 | molecular_function | UDP-glycosyltransferase activity |
| A | 0009718 | biological_process | anthocyanin-containing compound biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0033303 | biological_process | quercetin O-glucoside biosynthetic process |
| A | 0033485 | biological_process | cyanidin 3-O-glucoside biosynthetic process |
| A | 0047213 | molecular_function | anthocyanidin 3-O-glucosyltransferase activity |
| A | 0047893 | molecular_function | flavonol 3-O-glucosyltransferase activity |
| A | 0051555 | biological_process | flavonol biosynthetic process |
| A | 0080043 | molecular_function | quercetin 3-O-glucosyltransferase activity |
| A | 0102360 | molecular_function | daphnetin 3-O-glucosyltransferase activity |
| A | 0102425 | molecular_function | myricetin 3-O-glucosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE KMP A1456 |
| Chain | Residue |
| A | SER18 |
| A | PHE372 |
| A | HOH2304 |
| A | HIS20 |
| A | GLN84 |
| A | ILE87 |
| A | PHE121 |
| A | SER146 |
| A | HIS150 |
| A | GLN188 |
| A | PHE200 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE U2F A1457 |
| Chain | Residue |
| A | SER18 |
| A | THR19 |
| A | HIS20 |
| A | THR141 |
| A | TYR275 |
| A | SER277 |
| A | THR280 |
| A | SER306 |
| A | TRP332 |
| A | ALA333 |
| A | GLN335 |
| A | HIS350 |
| A | GLY352 |
| A | TRP353 |
| A | ASN354 |
| A | SER355 |
| A | GLU358 |
| A | PHE372 |
| A | ASP374 |
| A | GLN375 |
| A | HOH2200 |
| A | HOH2305 |
| A | HOH2306 |
Functional Information from PROSITE/UniProt
| site_id | PS00375 |
| Number of Residues | 44 |
| Details | UDPGT UDP-glycosyltransferases signature. WapQaeVLaheavgAFVTHCGwnSlweSVaggv.PLicrPffgDQ |
| Chain | Residue | Details |
| A | TRP332-GLN375 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:A0A0A1HA03 |
| Chain | Residue | Details |
| A | HIS20 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Charge relay => ECO:0000250|UniProtKB:A0A0A1HA03 |
| Chain | Residue | Details |
| A | ASP119 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16482224, ECO:0007744|PDB:2C9Z |
| Chain | Residue | Details |
| A | SER18 | |
| A | GLN84 | |
| A | HIS150 | |
| A | GLN188 | |
| A | GLY373 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 13 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:16482224, ECO:0007744|PDB:2C1Z |
| Chain | Residue | Details |
| A | THR19 | |
| A | SER355 | |
| A | GLU358 | |
| A | ASP374 | |
| A | GLN375 | |
| A | THR141 | |
| A | THR280 | |
| A | SER306 | |
| A | TRP332 | |
| A | ALA333 | |
| A | HIS350 | |
| A | TRP353 | |
| A | ASN354 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16482224, ECO:0007744|PDB:2C1Z |
| Chain | Residue | Details |
| A | HIS20 |
