Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A1507 |
| Chain | Residue |
| A | GLU498 |
| A | PTR501 |
| A | HOH2119 |
| A | HOH2123 |
| A | HOH2125 |
| B | GLU464 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A1508 |
| Chain | Residue |
| A | HOH2079 |
| A | HOH2082 |
| A | HOH2084 |
| A | ASN365 |
| A | ASP378 |
| A | HOH2078 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B1507 |
| Chain | Residue |
| A | GLU464 |
| B | GLU498 |
| B | PTR501 |
| B | HOH2064 |
| B | HOH2065 |
| B | HOH2068 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B1508 |
| Chain | Residue |
| B | ASN365 |
| B | ASP378 |
| B | HOH2023 |
| B | HOH2039 |
| B | HOH2040 |
| B | HOH2043 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE L3G A1506 |
| Chain | Residue |
| A | LEU247 |
| A | VAL255 |
| A | ALA267 |
| A | VAL268 |
| A | LYS269 |
| A | PHE281 |
| A | VAL297 |
| A | ILE310 |
| A | THR312 |
| A | GLU313 |
| A | PHE314 |
| A | MET315 |
| A | ASP322 |
| A | LEU367 |
| A | ASP378 |
| A | PHE379 |
| A | HOH2128 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE L3G B1506 |
| Chain | Residue |
| B | LEU247 |
| B | VAL255 |
| B | ALA267 |
| B | VAL268 |
| B | LYS269 |
| B | MET288 |
| B | VAL297 |
| B | ILE310 |
| B | THR312 |
| B | GLU313 |
| B | MET315 |
| B | ASP322 |
| B | LEU367 |
| B | ASP378 |
| B | PHE379 |
| B | LEU381 |
| B | HOH2071 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 23 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGAGQFGEVWmAtynkhtk...........VAVK |
| Chain | Residue | Details |
| A | LEU247-LYS269 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YIHrDLRAANILV |
| Chain | Residue | Details |
| A | TYR356-VAL368 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P08103","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ALA364 | |
| A | ASP360 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ALA364 | |
| B | ASP360 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ARG362 | |
| A | ASP360 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ARG362 | |
| B | ASP360 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ARG362 | |
| A | ASP360 | |
| A | ASN365 | |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ARG362 | |
| B | ASP360 | |
| B | ASN365 | |
