Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A1507 |
| Chain | Residue |
| A | GLU498 |
| A | PTR501 |
| A | HOH2166 |
| A | HOH2169 |
| A | HOH2171 |
| B | GLU464 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B1507 |
| Chain | Residue |
| B | HOH2088 |
| B | HOH2089 |
| B | HOH2096 |
| A | GLU464 |
| B | GLU498 |
| B | PTR501 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE L1G A1506 |
| Chain | Residue |
| A | LEU247 |
| A | ALA267 |
| A | LYS269 |
| A | PHE281 |
| A | ILE310 |
| A | THR312 |
| A | GLU313 |
| A | MET315 |
| A | ASP322 |
| A | LEU367 |
| A | ASP378 |
| A | PHE379 |
| A | HOH2173 |
| A | HOH2174 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE L1G B1506 |
| Chain | Residue |
| B | VAL255 |
| B | ALA267 |
| B | VAL268 |
| B | LYS269 |
| B | VAL297 |
| B | ILE310 |
| B | THR312 |
| B | GLU313 |
| B | MET315 |
| B | ASP322 |
| B | LEU367 |
| B | ALA377 |
| B | ASP378 |
| B | PHE379 |
| B | LEU381 |
| B | HOH2099 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 23 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGAGQFGEVWmAtynkhtk...........VAVK |
| Chain | Residue | Details |
| A | LEU247-LYS269 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YIHrDLRAANILV |
| Chain | Residue | Details |
| A | TYR356-VAL368 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | LEU361 | |
| B | LEU361 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLY248 | |
| A | THR270 | |
| B | GLY248 | |
| B | THR270 | |
| Chain | Residue | Details |
| A | LEU182 | |
| B | LEU182 | |
| Chain | Residue | Details |
| A | ILE189 | |
| B | ILE189 | |
| Chain | Residue | Details |
| A | THR391 | |
| B | THR391 | |
| Chain | Residue | Details |
| A | ASN442 | |
| B | ASN442 | |
| Chain | Residue | Details |
| A | GLU502 | |
| B | GLU502 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ALA364 | |
| A | ASP360 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ALA364 | |
| B | ASP360 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ARG362 | |
| A | ASP360 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ARG362 | |
| B | ASP360 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ARG362 | |
| A | ASP360 | |
| A | ASN365 | |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ARG362 | |
| B | ASP360 | |
| B | ASN365 | |
