2BWL

Murine angiogenin, phosphate complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001525	biological_process	angiogenesis
A	0001666	biological_process	response to hypoxia
A	0001938	biological_process	positive regulation of endothelial cell proliferation
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003723	molecular_function	RNA binding
A	0003779	molecular_function	actin binding
A	0004519	molecular_function	endonuclease activity
A	0004540	molecular_function	RNA nuclease activity
A	0004549	molecular_function	tRNA-specific ribonuclease activity
A	0005102	molecular_function	signaling receptor binding
A	0005507	molecular_function	copper ion binding
A	0005576	cellular_component	extracellular region
A	0005604	cellular_component	basement membrane
A	0005615	cellular_component	extracellular space
A	0005634	cellular_component	nucleus
A	0005730	cellular_component	nucleolus
A	0007417	biological_process	central nervous system development
A	0008201	molecular_function	heparin binding
A	0009303	biological_process	rRNA transcription
A	0017148	biological_process	negative regulation of translation
A	0019731	biological_process	antibacterial humoral response
A	0023052	biological_process	signaling
A	0030041	biological_process	actin filament polymerization
A	0030154	biological_process	cell differentiation
A	0030426	cellular_component	growth cone
A	0031410	cellular_component	cytoplasmic vesicle
A	0032311	cellular_component	angiogenin-PRI complex
A	0036417	biological_process	tRNA destabilization
A	0042803	molecular_function	protein homodimerization activity
A	0043025	cellular_component	neuronal cell body
A	0045087	biological_process	innate immune response
A	0048662	biological_process	negative regulation of smooth muscle cell proliferation
A	0050714	biological_process	positive regulation of protein secretion
A	0050830	biological_process	defense response to Gram-positive bacterium
A	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PO4 A1120

Chain	Residue
A	GLN12
A	HOH2080
A	HIS13
A	LYS40
A	VAL112
A	HIS113
A	PHE114
A	HOH2027
A	HOH2073
A	HOH2079

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 A1121

Chain	Residue
A	TYR6
A	LYS50
A	LYS54
A	ARG65

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Functional Information from PROSITE/UniProt

site_id	PS00127
Number of Residues	7
Details	RNASE_PANCREATIC Pancreatic ribonuclease family signature. CKdvNTF

Chain	Residue	Details
A	CYS39-PHE45

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:P03950

Chain	Residue	Details
A	HIS13

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P03950

Chain	Residue	Details
A	HIS113

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	LYS40

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Pyrrolidone carboxylic acid => ECO:0000250|UniProtKB:P03950

Chain	Residue	Details
A	GLN1

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1rbn

Chain	Residue	Details
A	HIS13
A	HIS113
A	LYS40
A	PHE114

---

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1rbn

Chain	Residue	Details
A	HIS13
A	HIS113
A	LYS40

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