2BWJ

Structure of adenylate kinase 5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004017	molecular_function	AMP kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0019205	molecular_function	nucleobase-containing compound kinase activity
A	0046034	biological_process	ATP metabolic process
B	0004017	molecular_function	AMP kinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006139	biological_process	nucleobase-containing compound metabolic process
B	0019205	molecular_function	nucleobase-containing compound kinase activity
B	0046034	biological_process	ATP metabolic process
C	0004017	molecular_function	AMP kinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006139	biological_process	nucleobase-containing compound metabolic process
C	0019205	molecular_function	nucleobase-containing compound kinase activity
C	0046034	biological_process	ATP metabolic process
D	0004017	molecular_function	AMP kinase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006139	biological_process	nucleobase-containing compound metabolic process
D	0019205	molecular_function	nucleobase-containing compound kinase activity
D	0046034	biological_process	ATP metabolic process
E	0004017	molecular_function	AMP kinase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006139	biological_process	nucleobase-containing compound metabolic process
E	0019205	molecular_function	nucleobase-containing compound kinase activity
E	0046034	biological_process	ATP metabolic process
F	0004017	molecular_function	AMP kinase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006139	biological_process	nucleobase-containing compound metabolic process
F	0019205	molecular_function	nucleobase-containing compound kinase activity
F	0046034	biological_process	ATP metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SO4 A1199

Chain	Residue
A	GLY19
A	HOH2123
A	HOH2124
A	GLY21
A	SER22
A	GLY23
A	LYS24
A	GLY25
A	HOH2120
A	HOH2121
A	HOH2122

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A1200

Chain	Residue
A	SER54
A	GLU55
A	HOH2125
B	SER138
B	LEU140
B	HOH2080

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A1201

Chain	Residue
A	ALA125

---

site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SO4 B1199

Chain	Residue
B	GLY19
B	PRO20
B	GLY21
B	SER22
B	GLY23
B	LYS24
B	GLY25
B	HOH2009
B	HOH2099
B	HOH2100
B	HOH2101

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B1200

Chain	Residue
A	HOH2042
B	ARG152

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 C1198

Chain	Residue
C	GLY19
C	GLY21
C	SER22
C	GLY23
C	LYS24
C	GLY25
C	HOH2003
C	HOH2005
C	HOH2084

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D1197

Chain	Residue
D	GLY19
D	GLY21
D	SER22
D	GLY23
D	LYS24
D	GLY25

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 E1198

Chain	Residue
E	GLY19
E	GLY21
E	SER22
E	GLY23
E	LYS24
E	GLY25
E	HOH2039
E	HOH2040

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL E1199

Chain	Residue
E	ALA125

---

site_id	BC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 F1199

Chain	Residue
F	GLY19
F	GLY21
F	SER22
F	GLY23
F	LYS24
F	GLY25
F	HOH2006
F	HOH2010
F	HOH2096
F	HOH2097

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL F1200

Chain	Residue
C	ARG66
F	ARG100
F	TYR156

---

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL F1201

Chain	Residue
F	ARG158

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE AMP B1201

Chain	Residue
B	GLU29
B	HIS39
B	HOH2102

---

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE AMP C1199

Chain	Residue
C	HIS39
C	HOH2086

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AMP F1202

Chain	Residue
F	GLU29
F	HIS39
F	HOH2098
F	HOH2099

---

Functional Information from PROSITE/UniProt

site_id	PS00113
Number of Residues	12
Details	ADENYLATE_KINASE Adenylate kinase signature. FLIDGYPRevkQ

Chain	Residue	Details
A	PHE93-GLN104

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1092
Details	Region: {"description":"Adenylate kinase 2","evidences":[{"source":"PubMed","id":"19647735","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	174
Details	Region: {"description":"NMP 2","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2005","submissionDatabase":"PDB data bank","title":"Crystal structure of adenylate kinase 5.","authoringGroup":["Structural genomics consortium (SGC)"]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	60
Details	Region: {"description":"LID 2","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2005","submissionDatabase":"PDB data bank","title":"Crystal structure of adenylate kinase 5.","authoringGroup":["Structural genomics consortium (SGC)"]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	96
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P00568","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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