Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003848 | molecular_function | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity |
| A | 0004156 | molecular_function | dihydropteroate synthase activity |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| A | 0042558 | biological_process | pteridine-containing compound metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PMM A1865 |
| Chain | Residue |
| A | THR597 |
| A | LYS807 |
| A | ARG842 |
| A | HIS844 |
| A | HOH2097 |
| A | HOH2115 |
| A | ARG598 |
| A | ASP636 |
| A | ASN655 |
| A | ILE657 |
| A | ASP755 |
| A | PHE760 |
| A | LEU801 |
| A | GLY803 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PMM A1866 |
| Chain | Residue |
| A | SER379 |
| A | GLU380 |
| A | PRO381 |
| A | MET382 |
| A | TYR383 |
| A | PHE390 |
| A | ASN392 |
| A | ASP434 |
| A | ARG463 |
| A | PHE465 |
| A | ASN698 |
| A | HOH2009 |
Functional Information from PROSITE/UniProt
| site_id | PS00792 |
| Number of Residues | 16 |
| Details | DHPS_1 Dihydropteroate synthase signature 1. ImAIFNaTpDSFsDgG |
| Chain | Residue | Details |
| A | ILE546-GLY561 | |
| site_id | PS00793 |
| Number of Residues | 14 |
| Details | DHPS_2 Dihydropteroate synthase signature 2. ESvIIDVGGcsTrP |
| Chain | Residue | Details |
| A | GLU586-PRO599 | |
| site_id | PS00794 |
| Number of Residues | 12 |
| Details | HPPK 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. DnGPRtiDLDIV |
| Chain | Residue | Details |
| A | ASP425-VAL436 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 310 |
| Details | Domain: {"description":"Pterin-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00334","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 318 |
| Details | Region: {"description":"DHPS"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WND1","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15826662","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2BMB","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15826662","evidenceCode":"ECO:0000305"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1aj0 |
| Chain | Residue | Details |
| A | ASN551 | |
| A | ARG598 | |
| A | ARG842 | |
