2BIW

Crystal structure of apocarotenoid cleavage oxygenase from Synechocystis, native enzyme

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0010436	molecular_function	carotenoid dioxygenase activity
A	0016121	biological_process	carotene catabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity
A	0102162	molecular_function	all-trans-8'-apo-beta-carotenal 15,15'-oxygenase activity
B	0010436	molecular_function	carotenoid dioxygenase activity
B	0016121	biological_process	carotene catabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
B	0046872	molecular_function	metal ion binding
B	0051213	molecular_function	dioxygenase activity
B	0102162	molecular_function	all-trans-8'-apo-beta-carotenal 15,15'-oxygenase activity
C	0010436	molecular_function	carotenoid dioxygenase activity
C	0016121	biological_process	carotene catabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
C	0046872	molecular_function	metal ion binding
C	0051213	molecular_function	dioxygenase activity
C	0102162	molecular_function	all-trans-8'-apo-beta-carotenal 15,15'-oxygenase activity
D	0010436	molecular_function	carotenoid dioxygenase activity
D	0016121	biological_process	carotene catabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
D	0046872	molecular_function	metal ion binding
D	0051213	molecular_function	dioxygenase activity
D	0102162	molecular_function	all-trans-8'-apo-beta-carotenal 15,15'-oxygenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A1492

Chain	Residue
A	HIS183
A	HIS238
A	HIS304
A	HIS484
A	HOH2089

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE B1492

Chain	Residue
B	HOH2079
B	HIS183
B	HIS238
B	HIS304
B	HIS484

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE C1492

Chain	Residue
C	HIS183
C	HIS238
C	HIS304
C	HIS484
C	HOH2121

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE D1492

Chain	Residue
D	HIS183
D	HIS238
D	HIS304
D	HIS484
D	HOH2052

---

site_id	AC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE 3ON A1491

Chain	Residue
A	PHE69
A	LEU130
A	THR136
A	TRP149
A	GLU150
A	GLY151
A	SER206
A	PHE236
A	HIS238
A	PHE303
A	TYR322
A	GLU370
A	PHE371
A	LEU400
A	HOH2008
A	HOH2035
A	HOH2064
A	HOH2084

---

site_id	AC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE 3ON B1491

Chain	Residue
B	PHE69
B	LEU130
B	THR136
B	TRP149
B	SER206
B	HIS238
B	PHE303
B	TYR322
B	LEU400
B	HOH2022
B	HOH2042
B	HOH2075

---

site_id	AC7
Number of Residues	15
Details	BINDING SITE FOR RESIDUE 3ON C1491

Chain	Residue
C	PHE69
C	PHE113
C	LEU130
C	THR136
C	TRP149
C	GLU150
C	GLY151
C	SER206
C	PHE236
C	HIS238
C	PHE303
C	TYR322
C	GLU370
C	PHE371
C	HOH2042

---

site_id	AC8
Number of Residues	15
Details	BINDING SITE FOR RESIDUE 3ON D1491

Chain	Residue
D	PHE69
D	VAL112
D	THR136
D	TRP149
D	GLU150
D	GLY151
D	PHE236
D	HIS238
D	GLY269
D	PHE303
D	GLU370
D	HOH2005
D	HOH2020
D	HOH2047
D	HOH2065

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15821095","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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