2BGK
X-Ray structure of apo-Secoisolariciresinol Dehydrogenase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0009807 | biological_process | lignan biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0051289 | biological_process | protein homotetramerization |
| A | 0102911 | molecular_function | (-)-secoisolariciresinol dehydrogenase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0009807 | biological_process | lignan biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0051289 | biological_process | protein homotetramerization |
| B | 0102911 | molecular_function | (-)-secoisolariciresinol dehydrogenase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. IssftagegvShvYTATKHAVlGLTtSLC |
| Chain | Residue | Details |
| A | ILE154-CYS182 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000269|PubMed:15653677, ECO:0000269|PubMed:16493463, ECO:0007744|PDB:2BGL, ECO:0007744|PDB:2BGM |
| Chain | Residue | Details |
| A | TYR167 | |
| B | TYR1167 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15653677, ECO:0007744|PDB:2BGL, ECO:0007744|PDB:2BGM |
| Chain | Residue | Details |
| A | GLY23 | |
| B | VAL1073 | |
| B | ASN1099 | |
| B | SER1104 | |
| B | SER1164 | |
| B | LYS1171 | |
| A | ASP47 | |
| A | VAL73 | |
| A | ASN99 | |
| A | SER104 | |
| A | SER164 | |
| A | LYS171 | |
| B | GLY1023 | |
| B | ASP1047 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0007744|PDB:2BGL, ECO:0007744|PDB:2BGM |
| Chain | Residue | Details |
| A | VAL200 | |
| B | VAL1200 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | TYR167 | |
| A | LYS171 | |
| A | SER153 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | LYS1171 | |
| B | SER1153 | |
| B | TYR1167 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | TYR167 | |
| A | ASN125 | |
| A | LYS171 | |
| A | SER153 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | LYS1171 | |
| B | TYR1167 | |
| B | ASN1125 | |
| B | SER1153 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | TYR167 | |
| A | LYS171 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | LYS1171 | |
| B | TYR1167 |
