2BE7

Crystal structure of the unliganded (T-state) aspartate transcarbamoylase of the psychrophilic bacterium Moritella profunda

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004070	molecular_function	aspartate carbamoyltransferase activity
A	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
A	0006221	biological_process	pyrimidine nucleotide biosynthetic process
A	0006520	biological_process	amino acid metabolic process
A	0009220	biological_process	pyrimidine ribonucleotide biosynthetic process
A	0016597	molecular_function	amino acid binding
A	0016740	molecular_function	transferase activity
A	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
A	0044205	biological_process	'de novo' UMP biosynthetic process
B	0004070	molecular_function	aspartate carbamoyltransferase activity
B	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
B	0006221	biological_process	pyrimidine nucleotide biosynthetic process
B	0006520	biological_process	amino acid metabolic process
B	0009220	biological_process	pyrimidine ribonucleotide biosynthetic process
B	0016597	molecular_function	amino acid binding
B	0016740	molecular_function	transferase activity
B	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
B	0044205	biological_process	'de novo' UMP biosynthetic process
C	0004070	molecular_function	aspartate carbamoyltransferase activity
C	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
C	0006221	biological_process	pyrimidine nucleotide biosynthetic process
C	0006520	biological_process	amino acid metabolic process
C	0009220	biological_process	pyrimidine ribonucleotide biosynthetic process
C	0016597	molecular_function	amino acid binding
C	0016740	molecular_function	transferase activity
C	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
C	0044205	biological_process	'de novo' UMP biosynthetic process
D	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
D	0006221	biological_process	pyrimidine nucleotide biosynthetic process
D	0009347	cellular_component	aspartate carbamoyltransferase complex
D	0046872	molecular_function	metal ion binding
E	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
E	0006221	biological_process	pyrimidine nucleotide biosynthetic process
E	0009347	cellular_component	aspartate carbamoyltransferase complex
E	0046872	molecular_function	metal ion binding
F	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
F	0006221	biological_process	pyrimidine nucleotide biosynthetic process
F	0009347	cellular_component	aspartate carbamoyltransferase complex
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 1108

Chain	Residue
D	CYS108
D	CYS113
D	CYS137
D	CYS140

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 1108

Chain	Residue
E	CYS108
E	CYS113
E	CYS137
E	CYS140

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 1108

Chain	Residue
F	CYS113
F	CYS137
F	CYS140
F	CYS108

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 311

Chain	Residue
A	SER53
A	THR54
A	ARG55
A	THR56
B	SER81

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 311

Chain	Residue
A	SER81
C	SER53
C	THR54
C	ARG55
C	THR56
C	HOH313

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 311

Chain	Residue
B	SER53
B	THR54
B	ARG55
B	THR56
B	HOH320
C	SER81

---

Functional Information from PROSITE/UniProt

site_id	PS00097
Number of Residues	8
Details	CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FfEaSTRT

Chain	Residue	Details
A	PHE49-THR56

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
D	CYS108
F	CYS113
F	CYS137
F	CYS140
B	GLY86
B	HIS107
B	PRO135
B	THR138
B	THR168
B	VAL230
B	PRO268
D	CYS113
B	ARG269
C	THR56
C	ARG57
C	GLY86
C	HIS107
C	PRO135
C	THR138
C	THR168
C	VAL230
C	PRO268
D	CYS137
C	ARG269
D	CYS140
E	CYS108
E	CYS113
E	CYS137
E	CYS140
F	CYS108

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1at1

Chain	Residue	Details
A	ARG106
A	THR56
A	HIS134
A	ARG55

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1at1

Chain	Residue	Details
B	ARG106
B	THR56
B	HIS134
B	ARG55

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1at1

Chain	Residue	Details
C	ARG106
C	THR56
C	HIS134
C	ARG55

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