2BB2

X-RAY ANALYSIS OF BETA B2-CRYSTALLIN AND EVOLUTION OF OLIGOMERIC LENS PROTEINS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005212	molecular_function	structural constituent of eye lens
A	0007601	biological_process	visual perception

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE BME A 176

Chain	Residue
A	LEU18
A	PRO21
A	CYS22
A	ASN24
A	GLU27
A	THR28

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BME A 177

Chain	Residue
A	PRO21
A	ASN49
A	CYS50

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	39
Details	Domain: {"description":"Beta/gamma crystallin 'Greek key' 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00028","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	44
Details	Domain: {"description":"Beta/gamma crystallin 'Greek key' 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00028","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	41
Details	Domain: {"description":"Beta/gamma crystallin 'Greek key' 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00028","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	42
Details	Domain: {"description":"Beta/gamma crystallin 'Greek key' 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00028","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Region: {"description":"Connecting peptide"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Site: {"description":"Not glycated","evidences":[{"source":"PubMed","id":"8954094","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	10
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) lysine; in vitro","evidences":[{"source":"PubMed","id":"8954094","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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