2B4H
Crystal Structure of the Rhesus Rotavirus VP5 Antigen Domain Dimer
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE TRS A 5001 |
| Chain | Residue |
| A | SER412 |
| A | ARG425 |
| B | SER412 |
| B | ARG425 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD B 1001 |
| Chain | Residue |
| B | PHE362 |
| B | ILE271 |
| B | ARG307 |
| B | ASP357 |
| B | SER359 |
| B | ALA361 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MPD A 2001 |
| Chain | Residue |
| A | HIS315 |
| A | TRP356 |
| A | HOH5110 |
| A | HOH5159 |
| B | VAL432 |
| B | GLU433 |
| B | HOH4058 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD A 3001 |
| Chain | Residue |
| A | THR335 |
| A | ASP336 |
| A | PHE337 |
| A | ARG441 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD B 4001 |
| Chain | Residue |
| B | HIS315 |
| B | THR317 |
| B | TRP356 |
| B | SER423 |
| B | HOH4064 |
| B | HOH4156 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Region: {"description":"Hydrophobic; possible role in virus entry into host cell","evidences":[{"source":"HAMAP-Rule","id":"MF_04132","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20375171","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Motif: {"description":"DGE motif; interaction with ITGA2/ITGB1 heterodimer","evidences":[{"source":"HAMAP-Rule","id":"MF_04132","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11112480","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Motif: {"description":"YGL motif; interaction with ITGA4","evidences":[{"source":"HAMAP-Rule","id":"MF_04132","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16298987","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
