2B3D
Crystal structure of Modulator of Drug activity B in complex with flavin adenine dinucleotide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003955 | molecular_function | NAD(P)H dehydrogenase (quinone) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008753 | molecular_function | NADPH dehydrogenase (quinone) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0003955 | molecular_function | NAD(P)H dehydrogenase (quinone) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008753 | molecular_function | NADPH dehydrogenase (quinone) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0034599 | biological_process | cellular response to oxidative stress |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE FAD A 1205 |
| Chain | Residue |
| A | PHE24 |
| A | THR34 |
| A | PRO79 |
| A | GLY80 |
| A | TRP81 |
| A | TRP82 |
| A | MET83 |
| A | THR135 |
| A | TRP136 |
| A | ASN137 |
| A | ALA138 |
| A | ALA25 |
| A | VAL182 |
| A | HOH1215 |
| A | HOH1250 |
| A | HOH1263 |
| A | HOH1334 |
| A | HOH1398 |
| B | THR98 |
| B | TYR119 |
| A | HIS26 |
| A | SER27 |
| A | ASN28 |
| A | GLY29 |
| A | GLN30 |
| A | LEU31 |
| A | ASN32 |
| site_id | AC2 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FAD B 1206 |
| Chain | Residue |
| A | THR98 |
| A | TYR119 |
| A | ARG190 |
| B | PHE24 |
| B | HIS26 |
| B | SER27 |
| B | ASN28 |
| B | GLY29 |
| B | GLN30 |
| B | LEU31 |
| B | ASN32 |
| B | THR34 |
| B | PRO79 |
| B | GLY80 |
| B | TRP81 |
| B | TRP82 |
| B | MET83 |
| B | THR135 |
| B | TRP136 |
| B | ASN137 |
| B | ALA138 |
| B | VAL182 |
| B | HOH1220 |
| B | HOH1224 |
| B | HOH1245 |
| B | HOH1260 |
| B | HOH1315 |
| B | HOH1347 |
| B | HOH1393 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P0AEY7 |
| Chain | Residue | Details |
| A | SER27 | |
| A | GLY80 | |
| A | TYR119 | |
| A | THR135 | |
| B | SER27 | |
| B | GLY80 | |
| B | TYR119 | |
| B | THR135 |
