2AQ4

Ternary complex of the catalytic core of REV1 with DNA and dCTP.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 301

Chain	Residue
A	DCP201
A	MG302
A	ASP362
A	ASP467
A	GLU468
P	DOC12

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 302

Chain	Residue
A	PHE363
A	ASP467
A	DCP201
A	MG301
A	ASP362

---

site_id	AC3
Number of Residues	23
Details	BINDING SITE FOR RESIDUE DCP A 201

Chain	Residue
A	HOH13
A	HOH15
A	HOH20
A	HOH49
A	HOH67
A	MG301
A	MG302
A	ARG324
A	LEU328
A	ASP362
A	PHE363
A	ASP364
A	CYS365
A	PHE366
A	PHE367
A	ALA401
A	SER402
A	TYR405
A	ARG408
A	ASN414
A	ASP467
A	LYS525
P	DOC12

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	23
Details	Region: {"description":"Interaction with target DNA"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16195463","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18275815","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00216","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18275815","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Site: {"description":"Interaction with target DNA"}

Chain

Residue

Details

---