Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS A 701 |
| Chain | Residue |
| A | TRP6 |
| B | ARG187 |
| B | ASN188 |
| B | HOH1063 |
| B | HOH1070 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMS A 702 |
| Chain | Residue |
| A | LYS70 |
| A | HOH1085 |
| B | HOH1059 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACY A 801 |
| Chain | Residue |
| B | GOL805 |
| A | HOH1149 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY A 802 |
| Chain | Residue |
| A | MET46 |
| A | LYS55 |
| A | HOH1137 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACY A 803 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ACY A 804 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 805 |
| Chain | Residue |
| A | ACY801 |
| B | LYS155 |
| B | VAL156 |
| B | ARG157 |
| B | HOH1067 |
| B | HOH1112 |
| site_id | AC8 |
| Number of Residues | 41 |
| Details | BINDING SITE FOR CHAIN C OF PEPTIDE INHIBITOR |
| Chain | Residue |
| A | TRP6 |
| A | ARG8 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | LYS45 |
| A | MET46 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | PHE53 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| B | ARG108 |
| B | LEU123 |
| B | ASP125 |
| B | GLY127 |
| B | ALA128 |
| B | ASP129 |
| B | ASP130 |
| B | LYS145 |
| B | MET146 |
| B | ILE147 |
| B | GLY148 |
| B | GLY149 |
| B | ILE150 |
| B | PHE153 |
| B | GLN161 |
| B | ILE172 |
| B | PRO181 |
| B | VAL182 |
| B | ILE184 |
| B | GLN192 |
| B | HOH1008 |
| B | HOH1018 |
| B | HOH1135 |
| C | HOH1013 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE64 | |
| B | ILE164 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by host => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE64 | |
| B | ILE164 | |
