Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE 2NC A 400 |
| Chain | Residue |
| A | ARG8 |
| A | PRO81 |
| A | ALA82 |
| A | ILE84 |
| A | ACY801 |
| A | HOH1011 |
| A | HOH1022 |
| A | HOH1031 |
| A | HOH1035 |
| A | HOH1042 |
| A | HOH1123 |
| A | LEU23 |
| A | HOH1138 |
| A | HOH1154 |
| B | ARG108 |
| B | ASP125 |
| B | GLY127 |
| B | ALA128 |
| B | ASP129 |
| B | ASP130 |
| B | ILE147 |
| B | GLY148 |
| A | ASP25 |
| B | GLY149 |
| B | ILE150 |
| B | PRO181 |
| B | HOH1005 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL A 701 |
| Chain | Residue |
| A | GLN18 |
| A | MET36 |
| A | SER37 |
| A | HOH1226 |
| B | THR112 |
| B | ILE113 |
| B | LYS114 |
| B | GLU165 |
| B | ILE166 |
| B | ALA167 |
| B | GLY168 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 702 |
| Chain | Residue |
| A | LYS45 |
| A | MET46 |
| A | PHE53 |
| A | HOH1002 |
| A | HOH1031 |
| A | HOH1118 |
| A | HOH1123 |
| A | HOH1225 |
| B | GLN161 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 705 |
| Chain | Residue |
| A | PRO1 |
| A | HIS69 |
| A | HOH1149 |
| A | HOH1215 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACY A 801 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 703 |
| Chain | Residue |
| B | GLU135 |
| B | LYS155 |
| B | ARG157 |
| B | VAL177 |
| B | PRO179 |
| B | HOH1148 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 704 |
| Chain | Residue |
| A | LEU5 |
| A | TRP6 |
| B | ARG187 |
| B | ASN188 |
| B | HOH1077 |
| B | HOH1088 |
| B | HOH1098 |
| B | HOH1121 |
| B | HOH1174 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE64 | |
| B | ILE164 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by host => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE64 | |
| B | ILE164 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| A | THR26 | |
| B | THR126 | |
| B | ASP125 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP125 | |
