Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE 0Q4 B 301 |
| Chain | Residue |
| A | ARG8 |
| A | GLY49 |
| A | ILE50 |
| A | PRO81 |
| A | ALA82 |
| A | ILE84 |
| B | ARG108 |
| B | LEU123 |
| B | ASP125 |
| B | GLY127 |
| B | ALA128 |
| A | ASP25 |
| B | ASP129 |
| B | ASP130 |
| B | LYS145 |
| B | MET146 |
| B | ILE147 |
| B | GLY148 |
| B | GLY149 |
| B | ILE150 |
| B | PRO181 |
| B | ALA182 |
| A | GLY27 |
| B | ILE184 |
| B | HOH1004 |
| B | HOH1011 |
| B | HOH1021 |
| B | HOH1040 |
| B | HOH1095 |
| B | HOH1177 |
| B | HOH1194 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | VAL32 |
| A | ILE47 |
| A | GLY48 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 501 |
| Chain | Residue |
| A | ASP60 |
| A | HOH1045 |
| A | HOH1047 |
| A | HOH1059 |
| A | HOH1076 |
| A | HOH1136 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 503 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| B | ARG141 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 502 |
| Chain | Residue |
| B | TRP106 |
| B | LYS155 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 504 |
| Chain | Residue |
| B | THR174 |
| B | ASN188 |
| B | HOH1034 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS A 601 |
| Chain | Residue |
| A | LYS45 |
| A | MET46 |
| B | GLN161 |
| B | ILE172 |
| B | GLN192 |
| B | HOH1003 |
| B | HOH1021 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY A 602 |
| Chain | Residue |
| A | THR12 |
| A | GLU65 |
| A | GLY68 |
| A | HOH1100 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 702 |
| Chain | Residue |
| A | ILE93 |
| A | GLY94 |
| A | HOH1147 |
| B | GOL701 |
| B | HOH1119 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 703 |
| Chain | Residue |
| A | GLU21 |
| A | GLU34 |
| A | ALA82 |
| A | ASN83 |
| A | HOH1024 |
| A | HOH1057 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 701 |
| Chain | Residue |
| A | GOL702 |
| B | GLU135 |
| B | ARG157 |
| B | VAL177 |
| B | GLY178 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE64 | |
| B | ILE164 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by host => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE64 | |
| B | ILE164 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| A | THR26 | |
| B | THR126 | |
| B | ASP125 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP125 | |
