Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE 2NC B 400 |
| Chain | Residue |
| A | ARG8 |
| A | VAL84 |
| A | HOH1191 |
| B | ARG108 |
| B | ASP125 |
| B | GLY127 |
| B | ALA128 |
| B | ASP129 |
| B | ASP130 |
| B | ILE147 |
| B | GLY148 |
| A | ASP25 |
| B | GLY149 |
| B | ILE150 |
| B | VAL182 |
| B | HOH1001 |
| B | HOH1006 |
| B | HOH1012 |
| B | HOH1022 |
| B | HOH1035 |
| B | HOH1042 |
| B | HOH1117 |
| A | GLY27 |
| B | HOH1135 |
| B | HOH1159 |
| A | ALA28 |
| A | ASP29 |
| A | GLY48 |
| A | ILE50 |
| A | THR80 |
| A | VAL82 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 500 |
| Chain | Residue |
| A | ASP60 |
| A | HOH1063 |
| A | HOH1111 |
| A | HOH1172 |
| A | HOH1211 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 503 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| A | HOH1132 |
| B | ARG141 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS A 601 |
| Chain | Residue |
| A | LYS45 |
| A | MET46 |
| A | HOH1003 |
| A | HOH1130 |
| B | GLN192 |
| B | CL502 |
| B | HOH1011 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DMS A 603 |
| Chain | Residue |
| A | GLN18 |
| A | LEU19 |
| A | LYS20 |
| B | GLU165 |
| B | GLY168 |
| B | LYS170 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DMS A 604 |
| Chain | Residue |
| A | ARG87 |
| A | ASN88 |
| A | THR91 |
| A | HOH1069 |
| B | LEU105 |
| B | TRP106 |
| B | ARG141 |
| B | HOH1072 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 701 |
| Chain | Residue |
| A | GLN18 |
| A | MET36 |
| A | SER37 |
| B | THR112 |
| B | ILE113 |
| B | GLU165 |
| B | ILE166 |
| B | ALA167 |
| B | GLY168 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 501 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 502 |
| Chain | Residue |
| A | DMS601 |
| B | THR174 |
| B | ASN188 |
| B | HOH1013 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 702 |
| Chain | Residue |
| B | GLU135 |
| B | LYS155 |
| B | ARG157 |
| B | VAL177 |
| B | GLY178 |
| B | HOH1181 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE64 | |
| B | ILE164 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by host => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE64 | |
| B | ILE164 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| A | THR26 | |
| B | THR126 | |
| B | ASP125 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP125 | |
