2AJR
Crystal structure of Possible 1-phosphofructokinase (EC 2.7.1.56) (tm0828) from Thermotoga Maritima at 2.46 A resolution
Replaces: 1O14Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008443 | molecular_function | phosphofructokinase activity |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| A | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| A | 0046835 | biological_process | carbohydrate phosphorylation |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0008443 | molecular_function | phosphofructokinase activity |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| B | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| B | 0046835 | biological_process | carbohydrate phosphorylation |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 320 |
| Chain | Residue |
| A | HIS255 |
| A | ALA292 |
| A | ARG295 |
| A | GLU297 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 320 |
| Chain | Residue |
| B | HIS255 |
| B | ALA292 |
| B | ARG295 |
| B | GLU297 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 321 |
| Chain | Residue |
| B | GLY40 |
| B | ASN44 |
| B | ASP12 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 321 |
| Chain | Residue |
| A | ASP12 |
| A | GLY40 |
| A | ASN44 |
| A | ASN95 |
Functional Information from PROSITE/UniProt
| site_id | PS00583 |
| Number of Residues | 25 |
| Details | PFKB_KINASES_1 pfkB family of carbohydrate kinases signature 1. GGkGiNVSiaLsKLGvpsvatgfvG |
| Chain | Residue | Details |
| A | GLY39-GLY63 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| A | LYS104 | |
| A | ASP261 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| B | LYS104 | |
| B | ASP261 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| A | ALA259 | |
| A | GLY258 | |
| A | GLY260 | |
| A | ASP261 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| B | ALA259 | |
| B | GLY258 | |
| B | GLY260 | |
| B | ASP261 |
