2AHE

Crystal structure of a soluble form of CLIC4. intercellular chloride ion channel

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005254	molecular_function	chloride channel activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005813	cellular_component	centrosome
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0005902	cellular_component	microvillus
A	0005911	cellular_component	cell-cell junction
A	0006811	biological_process	monoatomic ion transport
A	0006821	biological_process	chloride transport
A	0009986	cellular_component	cell surface
A	0015629	cellular_component	actin cytoskeleton
A	0015630	cellular_component	microtubule cytoskeleton
A	0016020	cellular_component	membrane
A	0016363	cellular_component	nuclear matrix
A	0016491	molecular_function	oxidoreductase activity
A	0030154	biological_process	cell differentiation
A	0030216	biological_process	keratinocyte differentiation
A	0030336	biological_process	negative regulation of cell migration
A	0030496	cellular_component	midbody
A	0030659	cellular_component	cytoplasmic vesicle membrane
A	0031410	cellular_component	cytoplasmic vesicle
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0034702	cellular_component	monoatomic ion channel complex
A	0034707	cellular_component	chloride channel complex
A	0035088	biological_process	establishment or maintenance of apical/basal cell polarity
A	0045177	cellular_component	apical part of cell
A	0048471	cellular_component	perinuclear region of cytoplasm
A	0051493	biological_process	regulation of cytoskeleton organization
A	0070062	cellular_component	extracellular exosome
A	0070161	cellular_component	anchoring junction
A	0071277	biological_process	cellular response to calcium ion
A	1902476	biological_process	chloride transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	Transmembrane: {"description":"Helical; Note=After insertion into the membrane","evidences":[{"source":"UniProtKB","id":"Q9Z0W7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Motif: {"description":"G-site","evidences":[{"source":"UniProtKB","id":"Q9Z0W7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O00299","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O00299","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9QYB1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9Z1Q5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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