2AHE
Crystal structure of a soluble form of CLIC4. intercellular chloride ion channel
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005254 | molecular_function | chloride channel activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005813 | cellular_component | centrosome |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0005902 | cellular_component | microvillus |
| A | 0005911 | cellular_component | cell-cell junction |
| A | 0006821 | biological_process | chloride transport |
| A | 0009986 | cellular_component | cell surface |
| A | 0015629 | cellular_component | actin cytoskeleton |
| A | 0015630 | cellular_component | microtubule cytoskeleton |
| A | 0016020 | cellular_component | membrane |
| A | 0016363 | cellular_component | nuclear matrix |
| A | 0030154 | biological_process | cell differentiation |
| A | 0030216 | biological_process | keratinocyte differentiation |
| A | 0030336 | biological_process | negative regulation of cell migration |
| A | 0030496 | cellular_component | midbody |
| A | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| A | 0035088 | biological_process | establishment or maintenance of apical/basal cell polarity |
| A | 0045177 | cellular_component | apical part of cell |
| A | 0048471 | cellular_component | perinuclear region of cytoplasm |
| A | 0051493 | biological_process | regulation of cytoskeleton organization |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0070161 | cellular_component | anchoring junction |
| A | 0071277 | biological_process | cellular response to calcium ion |
| A | 1902476 | biological_process | chloride transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Note=After insertion into the membrane","evidences":[{"source":"UniProtKB","id":"Q9Z0W7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Motif: {"description":"G-site","evidences":[{"source":"UniProtKB","id":"Q9Z0W7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O00299","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O00299","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9QYB1","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9Z1Q5","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
