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2AHC

Chorismate lyase with inhibitor Vanilate

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006744biological_processubiquinone biosynthetic process
A0008813molecular_functionchorismate lyase activity
A0016829molecular_functionlyase activity
A0042866biological_processpyruvate biosynthetic process
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006744biological_processubiquinone biosynthetic process
B0008813molecular_functionchorismate lyase activity
B0016829molecular_functionlyase activity
B0042866biological_processpyruvate biosynthetic process
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006744biological_processubiquinone biosynthetic process
C0008813molecular_functionchorismate lyase activity
C0016829molecular_functionlyase activity
C0042866biological_processpyruvate biosynthetic process
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0006744biological_processubiquinone biosynthetic process
D0008813molecular_functionchorismate lyase activity
D0016829molecular_functionlyase activity
D0042866biological_processpyruvate biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE VNL A 166
ChainResidue
AMET34
AARG76
AILE78
ALEU114
ALEU153
AGLU155
AHOH201

site_idAC2
Number of Residues10
DetailsBINDING SITE FOR RESIDUE VNL B 266
ChainResidue
BARG76
BILE78
BTHR92
BPRO113
BLEU114
BTHR154
BGLU155
BHOH301
BMET34
BTHR35

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE VNL C 366
ChainResidue
CARG76
CPRO113
CLEU114
CTHR154
CGLU155

site_idAC4
Number of Residues11
DetailsBINDING SITE FOR RESIDUE VNL D 466
ChainResidue
DMET34
DTHR35
DARG76
DILE78
DLEU80
DTHR92
DPRO113
DLEU114
DTHR154
DGLU155
DHOH501

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues16
DetailsBINDING: BINDING => ECO:0000269|PubMed:11455603, ECO:0000269|PubMed:16343413
ChainResidueDetails
ATHR35
CGLU77
CGLY115
CLEU156
DTHR35
DGLU77
DGLY115
DLEU156
AGLU77
AGLY115
ALEU156
BTHR35
BGLU77
BGLY115
BLEU156
CTHR35

224572

PDB entries from 2024-09-04

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