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2ADF

Crystal Structure and Paratope Determination of 82D6A3, an Antithrombotic Antibody Directed Against the von Willebrand factor A3-Domain

Functional Information from GO Data
ChainGOidnamespacecontents
H0002250biological_processadaptive immune response
H0003823molecular_functionantigen binding
H0005576cellular_componentextracellular region
H0016064biological_processimmunoglobulin mediated immune response
H0019814cellular_componentimmunoglobulin complex
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 H 1002
ChainResidue
AGLN1089
AARG1090
HLYS51
HSER71
HLEU72
HSER191

site_idAC2
Number of Residues8
DetailsBINDING SITE FOR RESIDUE SO4 L 1003
ChainResidue
LGLN27
LASP28
LHOH1079
LHOH1089
LHOH1138
HPRO14
HASN88
HSER118

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ACY A 1112
ChainResidue
APHE1060
APHE1104
ALYS1107
AHOH1121
AHOH1223

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE GOL H 1004
ChainResidue
HTHR93
HGLN110
HGLY111
HHOH1066
HHOH1147

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
ChainResidueDetails
LTYR191-HIS197

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PDB entries from 2024-10-30

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