2ABW
Glutaminase subunit of the plasmodial PLP synthase (Vitamin B6 biosynthesis)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000304 | biological_process | response to singlet oxygen |
| A | 0004359 | molecular_function | glutaminase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006541 | biological_process | glutamine metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0036381 | molecular_function | pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity |
| A | 0042819 | biological_process | vitamin B6 biosynthetic process |
| A | 0042823 | biological_process | pyridoxal phosphate biosynthetic process |
| B | 0000304 | biological_process | response to singlet oxygen |
| B | 0004359 | molecular_function | glutaminase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006541 | biological_process | glutamine metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0036381 | molecular_function | pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity |
| B | 0042819 | biological_process | vitamin B6 biosynthetic process |
| B | 0042823 | biological_process | pyridoxal phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 A 1101 |
| Chain | Residue |
| A | ASN136 |
| A | THR171 |
| A | SER173 |
| A | ASN180 |
| A | HOH1164 |
| B | LEU11 |
Functional Information from PROSITE/UniProt
| site_id | PS01236 |
| Number of Residues | 11 |
| Details | PDXT_SNO_1 PdxT/SNO family family signature. GLVIPGGESTT |
| Chain | Residue | Details |
| A | GLY46-THR56 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000250|UniProtKB:P37528 |
| Chain | Residue | Details |
| A | CYS87 | |
| B | CYS87 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Charge relay system => ECO:0000250|UniProtKB:P37528 |
| Chain | Residue | Details |
| A | HIS196 | |
| A | GLU198 | |
| B | HIS196 | |
| B | GLU198 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P37528 |
| Chain | Residue | Details |
| A | GLY52 | |
| A | ARG121 | |
| A | ILE153 | |
| B | GLY52 | |
| B | ARG121 | |
| B | ILE153 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bxr |
| Chain | Residue | Details |
| A | GLU198 | |
| A | CYS87 | |
| A | HIS196 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bxr |
| Chain | Residue | Details |
| B | GLU198 | |
| B | CYS87 | |
| B | HIS196 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bxr |
| Chain | Residue | Details |
| A | CYS87 | |
| A | HIS196 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1bxr |
| Chain | Residue | Details |
| B | CYS87 | |
| B | HIS196 |
