2A5S

Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GLU A 1001

Chain	Residue
A	HIS88
A	HOH1004
A	HOH1007
A	SER114
A	THR116
A	ARG121
A	GLY172
A	SER173
A	THR174
A	TYR214
A	ASP215

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16281028","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24462099","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27618671","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2A5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2A5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NF4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NF8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I56","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I57","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I58","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I59","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JTY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16281028","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24462099","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27618671","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2A5S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2A5T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NF4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NF8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I56","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I57","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I58","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JTY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---