29TE
The complex of A1AT-NHK with the ERAD misfolded glycoprotein checkpoint complex from Chaetomium thermophilum (EDEM:PDI heterodimer).
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0006091 | biological_process | generation of precursor metabolites and energy |
| A | 0008218 | biological_process | bioluminescence |
| A | 0036503 | biological_process | ERAD pathway |
| A | 0044322 | cellular_component | endoplasmic reticulum quality control compartment |
| B | 0003756 | molecular_function | protein disulfide isomerase activity |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005788 | cellular_component | endoplasmic reticulum lumen |
| B | 0006457 | biological_process | protein folding |
| B | 0015035 | molecular_function | protein-disulfide reductase activity |
| B | 0034976 | biological_process | response to endoplasmic reticulum stress |
| B | 0045454 | biological_process | cell redox homeostasis |
Functional Information from PROSITE/UniProt
| site_id | PS00194 |
| Number of Residues | 19 |
| Details | THIOREDOXIN_1 Thioredoxin family active site. LAeFFapWCGHCKaLapeY |
| Chain | Residue | Details |
| B | LEU42-TYR60 | |
| B | LEU377-TYR395 |
