28XB

Cryo-EM structure of the human UAP56-RNA - LENG8-PCID2-SEM1 complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
B	0003690	molecular_function	double-stranded DNA binding
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005643	cellular_component	nuclear pore
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0006368	biological_process	transcription elongation by RNA polymerase II
B	0006406	biological_process	mRNA export from nucleus
B	0016973	biological_process	poly(A)+ mRNA export from nucleus
B	0032991	cellular_component	protein-containing complex
B	0044615	cellular_component	nuclear pore nuclear basket
B	0045579	biological_process	positive regulation of B cell differentiation
B	0045814	biological_process	negative regulation of gene expression, epigenetic
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0048536	biological_process	spleen development
B	0070390	cellular_component	transcription export complex 2
B	1905457	biological_process	negative regulation of lymphoid progenitor cell differentiation
H	0000245	biological_process	spliceosomal complex assembly
H	0000346	cellular_component	transcription export complex
H	0000398	biological_process	mRNA splicing, via spliceosome
H	0003723	molecular_function	RNA binding
H	0003724	molecular_function	RNA helicase activity
H	0003729	molecular_function	mRNA binding
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005681	cellular_component	spliceosomal complex
H	0005687	cellular_component	U4 snRNP
H	0005688	cellular_component	U6 snRNP
H	0005737	cellular_component	cytoplasm
H	0006405	biological_process	RNA export from nucleus
H	0006406	biological_process	mRNA export from nucleus
H	0008186	molecular_function	ATP-dependent activity, acting on RNA
H	0008380	biological_process	RNA splicing
H	0016607	cellular_component	nuclear speck
H	0016887	molecular_function	ATP hydrolysis activity
H	0017070	molecular_function	U6 snRNA binding
H	0030621	molecular_function	U4 snRNA binding
H	0042802	molecular_function	identical protein binding
H	0043008	molecular_function	ATP-dependent protein binding

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO220-ASN237

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	345
Details	Domain: {"description":"PCI","evidences":[{"source":"PROSITE-ProRule","id":"PRU01185","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	173
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	28
Details	Motif: {"description":"Q motif"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	3
Details	Motif: {"description":"DECD box"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	7
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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