23CU
Cryo-EM structure of the MRGPRX4-miniGsq complex in the apo state, local
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. TGLsMLSAISTERCLsV |
| Chain | Residue | Details |
| R | THR108-VAL124 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"34789874","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7S8P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"34789874","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7S8P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 28 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"34789874","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7S8P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 18 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"34789874","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7S8P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 25 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"34789874","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7S8P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 24 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"34789874","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7S8P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 10 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"34789874","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7S8P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"34789874","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7S8P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
