21KT
Wnt3a signalosome extracellular complex
Functional Information from PROSITE/UniProt
| site_id | PS00246 |
| Number of Residues | 10 |
| Details | WNT1 Wnt-1 family signature. CKCHGLSGsC |
| Chain | Residue | Details |
| A | CYS203-CYS212 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Site: {"description":"Cleavage; by TIKI1 and TIKI2","evidences":[{"source":"PubMed","id":"22726442","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Lipidation: {"description":"O-palmitoleoyl serine; by PORCN","evidences":[{"source":"PubMed","id":"17141155","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24798332","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25771893","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | Region: {"description":"Wnt-binding","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 84 |
| Details | Repeat: {"description":"LDL-receptor class B 11"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 84 |
| Details | Repeat: {"description":"LDL-receptor class B 12"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 84 |
| Details | Repeat: {"description":"LDL-receptor class B 13"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"LDL-receptor class B 14"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 84 |
| Details | Repeat: {"description":"LDL-receptor class B 15"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 82 |
| Details | Domain: {"description":"EGF-like 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 96 |
| Details | Repeat: {"description":"LDL-receptor class B 16"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 84 |
| Details | Repeat: {"description":"LDL-receptor class B 17"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 88 |
| Details | Repeat: {"description":"LDL-receptor class B 18"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 84 |
| Details | Repeat: {"description":"LDL-receptor class B 19"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 82 |
| Details | Repeat: {"description":"LDL-receptor class B 20"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 82 |
| Details | Domain: {"description":"EGF-like 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 518 |
| Details | Region: {"description":"Beta-propeller 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI19 |
| Number of Residues | 538 |
| Details | Region: {"description":"Beta-propeller 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI20 |
| Number of Residues | 10 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22000856","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
