1ZVF
The crystal structure of 3-hydroxyanthranilate 3,4-dioxygenase from Saccharomyces cerevisiae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000334 | molecular_function | 3-hydroxyanthranilate 3,4-dioxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006569 | biological_process | L-tryptophan catabolic process |
| A | 0008198 | molecular_function | ferrous iron binding |
| A | 0009435 | biological_process | NAD+ biosynthetic process |
| A | 0019805 | biological_process | quinolinate biosynthetic process |
| A | 0034354 | biological_process | 'de novo' NAD+ biosynthetic process from L-tryptophan |
| B | 0000334 | molecular_function | 3-hydroxyanthranilate 3,4-dioxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006569 | biological_process | L-tryptophan catabolic process |
| B | 0008198 | molecular_function | ferrous iron binding |
| B | 0009435 | biological_process | NAD+ biosynthetic process |
| B | 0019805 | biological_process | quinolinate biosynthetic process |
| B | 0034354 | biological_process | 'de novo' NAD+ biosynthetic process from L-tryptophan |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI A 201 |
| Chain | Residue |
| A | HIS49 |
| A | GLU55 |
| A | HIS97 |
| A | HOH205 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI B 202 |
| Chain | Residue |
| B | HIS49 |
| B | GLU55 |
| B | HIS97 |
| B | HOH205 |
| B | HOH206 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI A 203 |
| Chain | Residue |
| A | CYS126 |
| A | CYS129 |
| A | CYS163 |
| A | CYS166 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI B 204 |
| Chain | Residue |
| B | CYS126 |
| B | CYS129 |
| B | CYS163 |
| B | CYS166 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03019","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {} |
| Chain | Residue | Details |
